Benzodiazepine's introduction into clinical revolutionized the treatment of psychiatric disorders. Now, a research group of experts in preliminary drug discovery, has developed a succinct and efficient multicomponent-assisted synthetic methodology assembling unexplored benzodiazepine collections, thus, enabling to examine new areas of biological applications.
The first comprehensive computer model to simulate the development of blood cells could help in the development of new treatments for leukaemia and lymphoma, say researchers at the University of Cambridge and Microsoft Research.
Antibodies are now established as therapeutics and indispensable in the research lab. In contrast to high-quality therapeutics, commercial antibodies used in research often do not properly function. Researchers demand that antibodies used in research should be made by recombinant DNA technology - just like therapeutic antibodies.
Researchers bioengineered the microstructures to be the same size, shape and stiffness as adult heart muscle cells, or cardiomyocytes, with the goal of releasing biologically active peptides that act as cardioprotective agents.
Lab-on-a-chip (LOC) systems have registered tremendous progress over the past 20 years. Myriad 'chip' schemes have already emerged, ranging from the lung-on-a-chip and heart-on-a-chip to the liver-on-a-chip and kidney-on-a-chip. However, until now, an ideal embryo-on-a-chip has not yet been developed due to challenges in condensing so many life factors inside a conventional LOC.
Researchers in Japan have succeeded in inducing human embryonic stem cells to self-organize into a three-dimensional structure similar to the cerebellum, providing tantalizing clues in the quest to recreate neural structures in the laboratory.