Researcher managed to clarify how DNA damage signaling works. The DNA molecule is chemically unstable giving rise to DNA lesions. That is why DNA damage detection, signaling and repair, collectively known as the DNA damage response, are needed. DNA repair consists of enzymes which find the damaged DNA and repair it. Some of them recognize the damaged bases and give signals to the other enzymes, which repair the DNA.
Using high-performance computing and genetic engineering to boost the photosynthetic efficiency of plants offers the best hope of increasing crop yields enough to feed a planet expected to have 9.5 billion people on it by 2050, researchers report in a new study.
Researchers have used a combination of metabolic engineering and directed evolution to develop a new, mutant yeast strain that could lead to a more efficient biofuel production process that would make biofuels more economically competitive with conventional fuels.
Researchers from the University of Copenhagen are the first in the world to develop a secure way of measuring the important protein apo-M. This could prove relevant for research into diseases such as diabetes, arteriosclerosis and sclerosis.
Scientists have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease.
A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.
Scientists develop world's first continuous purification method for valuable drugs. This will lead to significantly reduced production costs and to cheaper pharmaceuticals that are affordable for non-privileged health care systems.