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Biomedical research revealing secrets of cell behavior

Knowing virtually everything about how the body's cells make transitions from one state to another - for instance, precisely how particular cells develop into multi-cellular organisms - would be a major jump forward in understanding the basics of what drives biological processes.

Posted: Jul 1st, 2013

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3-D genomics shape up

New studies detail breakthroughs in his research on protein-DNA recognition. The findings may have profound implications for furthering research into cancer and other genetically based diseases.

Posted: Jun 28th, 2013

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Researchers develop powerful new technique to study protein function

The advance should allow deeper insights into protein function, Chase says, "because we can only get a true understanding of what that single protein does when we isolate its function." There was no tool to do this. Cover art uses a worm jigsaw puzzle to illustrate how knockdown strategies have evolved to achieve more cell-type specificity, culminating in the new approach, which can restrict knockdown to a single cell type.

Posted: Jun 19th, 2013

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Inventor patents anti-cholesterol formula

Senior Brandeis research scientist Daniel Perlman has discovered a way to make phytosterol molecules from plants dispersible in beverages and foods that are consumed by humans, potentially opening the way to dramatic reductions in human cholesterol levels.

Posted: Jun 18th, 2013

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Researchers engineer synthetic pathways for new antibacterial treatments

The project BASYNTHEC ('Bacterial synthetic minimal genomes for biotechnology') launched in 2010 with almost EUR 3 million in EU funding. It sought to develop a model-based approach for engineering B. subtilis and create synthetic modules for producing metabolites and proteins of interest. Ultimately, the research could lead to new antimicrobial treatments for bacterial infections.

Posted: Jun 18th, 2013

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Printing artificial bone

Researchers develop method to design synthetic materials and quickly turn the design into reality using computer optimization and 3-D printing.

Posted: Jun 17th, 2013

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Mapping translation sites in the human genome

Researchers at Arizona State University's Biodesign Institute have produced the first genome-wide investigation of cap-independent translation, identifying thousands of mRNA sequences that act as Translation Enhancing Elements (TEEs), which are RNA sequences upstream of the coding region that help recruit the ribosome to the translation start site.

Posted: Jun 17th, 2013

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