Researchers at the University of Minnesota's Department of Integrative Biology and Physiology and the Lillehei Heart Institute have utilized molecular genetic engineering to optimize heart performance in models of diastolic heart failure by creating an optimized protein that can aid in high-speed relaxation similar to fast twitching muscles.
MIT engineers have created genetic circuits in bacterial cells that not only perform logic functions, but also remember the results, which are encoded in the cell's DNA and passed on for dozens of generations.
Genes relocated from their correct position in the nucleus cause them to malfunction and this may lead to the heart, blood vessels and muscles breaking down. This new discovery by A*STAR scientists may be the key to finding new cures in the future.
Prof. Eran Halperin has found that advances in DNA sequencing carry with them an enormous risk - the theft of personal information from genetics databases poses a serious threat to privacy. He urges that new legislation concerning the maintenance of private and public databases, as well as anti-genetic-discrimination laws, should be drafted.
Researchers from the Polytechnic University of Catalonia have developed a technique that improves and cuts the cost of a technique called electroporation, which involves opening pores in cell membranes using an electric field to introduce substances like drugs and DNA.
Researchers propose a DNA chip with 32 polymorphisms to be used for diagnosing, but also for calculating genetic susceptibility to different variables, including how well the patient is responding well to drugs or normalisation of symptoms.
The Human TFIID is a megadalton-sized multiprotein complex composed of TATA-box-binding protein (TBP) and 13 TBP-associated factors (TAFs). Despite its crucial role, the detailed architecture and assembly mechanism of TFIID remain elusive.
A research team in Japan exploring the functions of messenger ribonucleic acid (mRNA) - a molecule that encodes the chemical blueprint for protein synthesis - has discovered a way to take a close look at the temperature distribution inside living cells. This discovery may lead to a better understanding of diseases, such as cancer, which generate extraordinary intracellular heat.