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Enzyme 3D map could lead to more effective drugs (w/video)

Researchers have completed a 3-D map of an enzyme called Proline utilization A (PutA). PutA facilitates metabolism by adding oxygen to molecules. Mapping this enzyme will give researchers a better understanding of its function, which could help drug manufacturers create more effective drugs.

Posted: May 13th, 2014

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Patient stem cells used to make 'heart disease-on-a-chip'

Scientists have merged stem cell and 'organ-on-a-chip' technologies to grow, for the first time, functioning human heart tissue carrying an inherited cardiovascular disease. The research appears to be a big step forward for personalized medicine, as it is working proof that a chunk of tissue containing a patient's specific genetic disorder can be replicated in the laboratory.

Posted: May 11th, 2014

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Bone marrow-on-a-chip unveiled (w/video)

The latest organ-on-a-chip from Harvard's Wyss Institute for Biologically Inspired Engineering reproduces the structure, functions and cellular make-up of bone marrow, a complex tissue that until now could only be studied intact in living animals.

Posted: May 5th, 2014

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Functioning of aged brains and muscles in mice made younger

Harvard Stem Cell Institute researchers have shown that a protein they previously demonstrated can make the failing hearts in aging mice appear more like those of young health mice, similarly improves brain and skeletal muscle function in aging mice.

Posted: May 5th, 2014

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How do our cells move? Liquid droplets could explain (w/video)

Scientists have discovered a new relationship between the three-dimensional shape of the cell and its ability to migrate. The work has important implications for the fundamental understanding of cell movement and for practical applications like tissue engineering.

Posted: May 2nd, 2014

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