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Key factor identified in gene silencing

Ubiquitinated histone gene silencing is vital in embryo development and goes awry in some cancers.

Aug 31st, 2017

Placenta-on-a-chip: Microsensor simulates malaria in the womb to develop treatments

By combining microbiology with engineering technologies, researchers are developing a first-of-its-kind 3D model that uses a single microfluidic sensing chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies.

Aug 29th, 2017

New open-source software for analyzing intact proteins

'Informed-Proteomics' eases top-down proteomics.

Aug 29th, 2017

LEGO-like proteins revealed

LEGO-like assemblies should have formed relatively frequently during evolution, according to scientists.

Aug 28th, 2017

Single-nucleus RNA sequencing, droplet by droplet

DroNc-Seq - a technology that merges single-nucleus RNA sequencing with microfluidics - brings new scale to gene expression studies in complex tissues.

Aug 28th, 2017

CLAMP's dual duties may make it model for studies of protein function in context

New research on a crucial protein in fruit flies provides a clear model for a fundamental question in biology that's significant for drug development in particular: What influences the exact same protein to coordinate a vital molecular process on one chromosome but an entirely different one on another chromosome?

Aug 28th, 2017

Researchers unlock regenerative potential of cells in the mouse retina

Researchers use a clue from zebrafish to discover the cues that reprogram Muller glia into retinal neurons.

Aug 28th, 2017

E. coli tripeptide production model reveals surprising complexity

The incredible complexity of a single-celled organism is revealed by a computer model of protein production.

Aug 25th, 2017

The science of fluoride flipping

A new imaging technique helps researchers study tiny, time-sensitive biological processes - the crucial underpinnings of human health and disease.

Aug 23rd, 2017

DNA sensor system developed for specific and sensitive measurement of cancer-relevant enzyme activity

The development of DNA sensor systems is of great importance for advances in medical science. Now another piece of the puzzle for the development of personalized medicine has been found with the results of a highly sensitive monitoring of cancer-related topoisomerase II enzymes.

Aug 23rd, 2017

Spinning plant waste into carbon fiber for cars, planes

Researchers report transforming lignin into carbon fiber to produce a lower-cost material strong enough to build car or aircraft parts.

Aug 23rd, 2017

Treating arthritis with algae

When chemically modified, this 'alginate' reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis.

Aug 23rd, 2017

Quantum ruler for biomolecules

Physicists measure molecular electronic properties of vitamins.

Aug 22nd, 2017

A tougher dental restoration composite

Scientists developed a new dental restoration composite that proves more durable than the conventional material.

Aug 22nd, 2017

Biophysics explains how immune cells kill bacteria

A new data analysis technique, moving subtrajectory analysis, defines the dynamics and kinetics of key molecules in the immune response to an infection. These biophysical descriptions are expected to clarify the TCR microcluster, an essential assembly for a T cell to initiate its attack on a pathogen.