Scientists have developed a brain implant that essentially melts into place, snugly fitting to the brain's surface. The technology could pave the way for better devices to monitor and control seizures, and to transmit signals from the brain past damaged parts of the spinal cord.
Using easily prepared gold nanocages that are able to escape from the blood stream and accumulate in tumors, a team of investigators from the Washington University in St. Louis has shown that they can use laser light to kill human tumors in mice.
Researchers have long known that certain peptides are capable of killing cells by inserting themselves into the cell membranes and disrupting normal membrane structure and function. Now, researchers have learned how to deliver these cytotoxic peptides to tumor cells using self-assembling nanofibers that can slip into cancer cells and allow the toxic peptides to do their job from inside the cell.
One of the promises of nanoparticles as delivery agents for cancer therapeutics is that they will attack tumors while sparing healthy tissue from the damage normally associated with today's anticancer therapies. That promise is closer to realization thanks to the results of a study in which tumor-bearing mice were treated with a single dose of radioactive gold nanoparticles.
A multi-institutional team of researchers and clinicians has published the first proof that a targeted nanoparticle can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off the production of an important cancer protein using a mechanism known as RNA interference (RNAi).
The U.S. Commerce Department's National Institute of Standards and Technology (NIST) today announced a new competition for high-risk, high-reward research funding under the Technology Innovation Program (TIP). The new TIP competition offers cost-shared funding for innovative research on 'Manufacturing and Biomanufacturing: Materials Advances and Critical Processes'.
Many advances in energy, green chemistry, and human health must start with understanding the movement of electrons - making frame-by-frame movies of changing molecular bonds during chemical reactions, or the correlated behavior of electrons in complex solids. This will only be possible by freezing time within a few quintillionths of a second.
Researchers have evidenced a basic general mechanism describing how filamentous proteins assemble into ribbon like structures, the so-called Amyloid fibrils. Combining experiments and theory, they could explain how denatured milk proteins assemble into ribbon like structures composed of up to five filaments.
The EC NanoCom project has opened a web based industrial consultation to discover the key success factors in exploiting pre-competitive research. We are encouraging all nanotech companies to contribute to this study, which will help to influence the debate on the best mechanisms of commercialisation for nanotechnologies.