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Targeted nanoparticles destroy prostate tumors

Biodegradable polymer nanoparticles, linked to a protein-binding nucleic acid known as an aptamer and loaded with the anticancer agent docetaxel, can target and kill prostate tumors growing in mice. Using this targeted nanoparticle to deliver docetaxel appears to reduce the toxic side effects associated with this drug.

Posted: Apr 24th, 2006

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Nano machine switches between biological and silicon worlds

Scientists have created a molecular switch that could play a key role in thousands of nanotech applications. The Mol-Switch project successfully developed a demonstrator to prove the principle, despite deep scepticism from specialist colleagues in biotechnology and biophysics.

Posted: Apr 24th, 2006

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Dip-pen lithography creates active protein nanoarrays

Arrays of proteins attached to solid surfaces have become important tools in drug discovery and cancer diagnostics, but in general, the immobilized proteins themselves are inactivated by the processes used to create these arrays. Now, however, researchers at Northwestern University have used dip-pen nanolithography to create arrays of antibodies that retain their ability to bind to their biological substrates.

Posted: Apr 17th, 2006

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Crystal sieves, born anew

The porous, sieve-like minerals known as zeolites have been used for decades in purifiers, filters and other devices. Yet creating and refining a new type of zeolite is still a matter of sophisticated trial and error: no one has been able to figure out exactly how the crystals form, even in the laboratory.

Posted: Apr 17th, 2006

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Laser wave drives electrons in chemical bonds

Researchers have demonstrated that the detailed shape of the electric field inside a short light pulse can be used to control the motion of electrons involved in chemical bonding and to change the outcome of a simple chemical reaction.

Posted: Apr 13th, 2006

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