To overcome a built-in mechanism that makes tumors resistant to radiation resistance, researchers have developed a nanoparticle formulation that interferes with the resistance mechanism, and as a result, increases the efficacy of radiation therapy in a mouse model of head and neck cancer.
Researchers at Harvard Medical School and the Massachusetts Institute of Technology have developed a strategy for identifying what could be called tumor uptake molecules for use on nanoparticles. This new class of tumor-targeting agents boosts the amount of drug-loaded nanoparticles that get into cancer cells.
One of the ways in which cancer cells evade anticancer therapy is by producing a protein that pumps drugs out of the cell before these compounds can exert their cell-killing effects. A research team at Northwestern University has found that biocompatible iron oxide-titanium dioxide nanoparticles can bypass this pump and enable DNA-damaging anticancer drugs to reach the cell nucleus.
Using technologies common to the semiconductor industry, a team of investigators at the University of North Carolina at Chapel Hill and Liquidia Technologies has created a polymer nanoparticle that can encapsulate large loads of therapeutic molecules that may have use in treating prostate cancer.
A collaborative effort between researchers at Stanford University and Xiamen University in China has produced a stable, biocompatible quantum dot that appears to have the desired set of properties needed for biomedical imaging.
By combining a nanoparticle that is readily visible in X-ray computed tomography (CT) scans with a molecule that targets tumor lymph vessels and other tumor tissues, a research team from the University of California, San Diego (UCSD) and the Sanford-Burnham Medical Research Institute has developed a new imaging agent that provides high-fidelity CT images of tumors and their edges.
It is so small that it cannot be seen by the naked eye - but a tiny Chinese New Year greetings card created by the University of Glasgow represents the huge potential for China to profit from Scottish innovation.
Five scientists from the SUNCAT Center for Interface Science and Catalysis, at SLAC National Accelerator Laboratory and Stanford's Department of Chemical Engineering, have a solution for those who design new chemical catalysts: They made an app.
Scientists have discovered that a superlattice phase-change film multilayered using germanium-tellurium alloy sub-layers and antimony-tellurium alloy sub-layers with aligned orientation axes has a magnetoresistance effect in excess of 2000% in a temperature range from room temperature to around 150 C.
When a pebble is dropped onto the surface of a pond, a droplet of water bounces up from the surface. The same thing happens when a focussed laser-beam strikes the surface of a thin metal film - the metal can be locally melted by the laser light and it can bounce up from the metal surface as a metallic droplet. Researchers now show that this phenomenon can be used to make nanoscale metallic droplets.
Researchers at Eindhoven University of Technology (TU/e) have succeeded in monitoring and controlling a molecular self-assembly process via different pathways. While it was formerly thought that the molecules form the right structure by themselves, this research shows that the assembly process can follow different pathways yielding different structures; in this case polymer chains with left- and right-handed helical directions.