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Nanotechnology Spotlight

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Showing Spotlights 1137 - 1144 of 2023 in category (newest first):


New modality of force microscopy advances non-destructive subsurface characterization techniques

ultrasonic_force_microscopyIn characterizing materials, especially live biological specimen such as cells, it is important not only to be able to explore the surface but also any subsurface structures and properties - without damaging or destroying the sample and for hard and soft materials alike. For example, many synthesized nanoparticles can readily get inside a cell. Therefore studying the cell surface, while useful, can provide little or no knowledge about the particles hidden in the interior of the cell. Another example is the detection of nanoscale defects in nanofabricated structures such as those made by electron beam lithography; or the detection of embedded cracks and voids in nanocomposite materials. Researchers have now shown that an atomic force microscope can obtain a range of surface and subsurface information by making use of the nonlinear nanomechanical coupling between the probe and the sample.

Posted: Jan 18th, 2010

Nanotechnology wool fabric combines multifunctionality with comfort

nanocoated_wool_fiberOne important aspect of clothing comfort is thermo-physiological comfort. By adjusting the transport of heat and moisture through a fabric, thermo-physiological comfort can keep people comfortable with regard to temperature and moisture. Some hydrophobic fabrics have deficiencies in this area. Take wool. Wool is one of the best insulating fibers known to man - while at the same time being light and soft. The quality that distinguishes wool fibers is the presence of a fatty, water-repellent outer layer that surrounds each fiber. Therefore, the water absorption and sweat venting properties of wool fiber are not very good, which affects the wearing comfort of wool textiles. The wool hydrophobic surface layer is also a barrier to anticrease finishing, dyeing, and grafting of hydrophilic agents, which is an issue in trying to add smart functionalities to wool fabrics. Researchers have now developed a simple method for fabricating environmentally stable superhydrophilic wool fabrics. They applied silica sols to natural wool fibers to form an ultrathin layer on the surface of the fibers.

Posted: Jan 15th, 2010

Communicating nanotechnology

microphoneExperts and the public generally differ in their perceptions of technology risk. While this might be due to social and demographic factors, it is generally assumed by scientists who conduct risk research that experts' risk assessments are based more strongly on actual or perceived knowledge about a technology than lay people's risk assessments. Nevertheless, whether the risks are real or not, the public perception of an emerging technology will have a major influence on the acceptance of this technology and its commercial success. If the public perception turns negative, potentially beneficial technologies will be severely constrained as is the case for instance with gene technology. It is not surprising that a new study found that, in general, nanoscientists are more optimistic than the public about the potential benefits of nanotechnology. What is surprising though, is that, for some issues related to the environmental and long-term health impacts of nanotechnology, nanoscientists seem to be significantly more concerned than the public. Arguing that risk communication on nanotechnologies requires target-specific approaches, a group of researchers in Germany advocate the development of communication strategies that help people to comprehend nanotechnology, to differentiate between the fields of application and to gain an understanding of the cause and effect chains.

Posted: Jan 14th, 2010

Trying to understand the interaction of nanoparticles with blood

bloodEmerging nanotechnology applications in the fields of medicine and biology often involve the use of nanoparticles for probing biological processes and structures or for constructing sophisticated nanoscale drug delivery mechanisms. Nanoparticles are already being used with dramatic success in biomedical applications. However, relatively little is known about the potential biological risks from these nanoparticle applications inside the body. The identity of nanoparticles in a biological medium, in terms of their interaction with that medium, is largely determined by the proteins that dress the particles. Since many of the toxic and therapeutic uses of nanoparticles involve the introduction of nanoparticles into the bloodstream of humans and other animals, it is particularly important to know how nanoparticles interact with blood proteins. New research performed in the Polymers Division at the National Institute of Standards and Technology (NIST) directly addresses this issue and explores the effects of nanoparticle size (5nm to 100nm) and a whole range of important blood proteins.

Posted: Jan 13th, 2010

Simple DNA nanomachine is capable of continuous rotation

dna_nanomachineA very promising field of nanomotor research are DNA nanomachines. These are synthetic DNA assemblies that switch between defined molecular shapes upon stimulation by external triggers. They can be controlled by a variety of methods that include pH changes and the addition of other molecular components, such as small molecule effectors, proteins and DNA strands. Researchers have now designed and built a simple DNA machine that is capable of continuous rotation with controlled speed and direction - a function that might be very useful for example for molecular transport. This machine is driven by an externally controlled electric field. When this field is oscillated between four directions, it continuously reorients a rotor DNA that is asymmetrically attached to a DNA axle.

Posted: Jan 12th, 2010

Molecular capture with protein nanotechnology

protein_nanotubeIn many biomedical applications, protein nanotubes present several advantages over nanospheres. The layer-by-layer (LbL) deposition technique for the preparation of protein nanotubes has attracted considerable attention because of their potential nanotechnology applications in enzymatic nanocatalysts, bioseparation nanofilters, and targeting nanocarriers. A drawback is that in template synthesis the extraction process often results in physical deformation of the nanotubes. Researchers in Japan have now developed a new procedure using specific solvent and freeze-drying technique. They describe for the first time molecular capturing properties of protein nanotubes with a controllable affinity and size selectivity.

Posted: Jan 11th, 2010

Highly effective single-protein nanocapsules improve prospects for protein therapies

protein_nanocapsuleProteins are the most important molecules inside our body. There are thousands of proteins in a single cell alone and they control our physiological reactions, metabolism, cellular information flow, defense mechanisms - pretty much everything. No wonder then that most human diseases are related to the malfunctioning of particular proteins. In contrast to gene therapy - where a gene is placed inside a cell to either replace a defective gene or to increase the amount of a specific gene in order to produce a higher amount of a desired protein - protein therapy works by directly delivering well-defined and precisely structured proteins into the cell to replace the dysfunctional protein. The problem with protein therapy, which limits its practical use in medicine, is the mode of delivery. Scientists have now demonstrated a general, effective, low-toxicity intracellular protein delivery system based on single-protein nanocapsules.

Posted: Jan 8th, 2010

Innovative Atomic Force Microscopy - bridging the gap to real world investigation

afmAfter two decades of evolution, Atomic Force Microscopy (AFM) has established its strong existence in the material science research field with its nanoscale resolution. Of the systems out in the market, the innovative XE-AFMs have overcome the non-linearity and non-orthogonality problems associated with traditional piezoelectric tube based AFMs. Active in both research and industrial applications including hard-disk, microchip fabrication, and quality control, the XE series has been widely adopted in the nanometrology field. The most recent addition to the XE family, the XE-Bio, has integrated the high resolution of AFM imaging and non-invasiveness capabilities Scanning Ion Conductance Microscopy with the versatility of advanced optical microscopy techniques such as scanning confocal microscopy, FRET and TIRF. Therefore, the XE-Bio is able to correlate the highest possible spatial resolution with dynamic functionality studies on live biological samples.

Posted: Jan 7th, 2010