Numerous previous research results have shown that gold nanorods (Au NRs) are able to effectively kill tumors upon irradiation with high laser doses, leading to hyperthermia-induced destruction of cancer cells (photodynamic therapy, PTT). In new work, researchers have demonstrated for the first time that bare gold nanorods alone can exert unprecedented photodynamic therapeutic (PDT) effects to result in cancer cellular deaths at low laser doses. Moreover, it appears that Au NRs-mediated PDT effects are far more effective in destruction of tumors in mice than the Au NRs-mediated PTT effects.
External stimuli, such as light, mechanical force, magnetic field, electrical field and electrochemical potential, are all driving forces that can be utilized to modulate the structure or conformation of molecules, and therefore to affect the performance of functional molecular devices. In new work, researchers take advantage of synergetic modulation by multiple external controls to explore multi-modulable molecular devices with the help of chemical tailoring, which have not been addressed so far.
A conventional optical microscope equipped with an oil immersion objective can resolve objects no smaller than about 200 nanometers - a restriction known as the diffraction limit. The diffraction limit, which typically is half the width of the wavelength of light being used to view the specimen, represents the fundamental limit of optical imaging resolution. Breaking this limit is possible by very sophisticated techniques and costly instrumentation. Now, though, researchers in Switzerland have found that when putting a transparent dielectric particle on top of an object with nanoscale features, details of that object with a size as small as one fourth of the diffraction limit can be resolved using a conventional microscope objective.
In the area of development cooperation which, like disaster relief, is often confronted with demands and scenarios that are hard to predict, nanotechnology based solutions can offer interesting perspectives for medical care, water treatment, agriculture and food, as well as rural infrastructure development in developing countries. A publication aims to inform managers and staff working in emergency response services and development cooperation as well as related institutions about the innovation potential of nanotechnology for their respective fields of work, and to highlight areas of overlap. The 84-page brochure also addresses companies and industry representatives that are already operating in this area or are interested in tapping in to this market.
Here are the 10 most popular Nanowerk Nanotechnology Spotlight articles of 2013. This year, the list includes nanotechnology in sports equipment, nanogenerators for energy harvesting, electronic skin, stealth coatings, green battery components, wearable textile batteries, two-dimensional materials beyond graphene, medical microrobots for drug delivery, chips inside cells to feel the pressure, and a list of graphene manufcaturers.
Measuring and mapping mechanical properties of live cells is of high importance in today's biological research. raditionally, force spectroscopy and force volume are the most commonly used modes to quantitatively measure mechanical forces at the nanometer scale. Unfortunately, both techniques have suffered from slow acquisition speed and a lack of automated tools to analyze the hundreds to thousands of curves required for good statistics. This application note reviews recent progress in mapping the properties of soft samples such as cells and gels with force volume and PeakForce QNM and the use of the newest NanoScope and NanoScope Analysis features to collect and analyze the data from these techniques.
Following extensive research in the field of bionano-interfaces, it is now well understood that the primary interaction of biological species with nanoparticles is strongly dependent to the long-lived protein corona, i.e. a strongly adsorbed protein layer at the surface of nanoparticles. The amount, composition, and exposure site of the associated proteins in the long-lived protein corona can define the biological response to the nanoparticles and hence reveal their biological fate. Scientists have now shown that laser plasmonic heat induction leads to significant changes in the protein corona composition at the surface of gold nanorods.
In microbial fuell cells, the anode material as the medium of electron transfer and as the support for biofilm formation is a key component that determines the effectiveness and efficiency of power generation. Generally, the anode will perform better if the anode material has a greater specific surface area and higher affinity for living bacterial cells. The direct carbonization of low-cost and naturally available materials provides a potential alternative to commercial anodes with high specific surface area. In new work, scientists demonstrate a new procedure to generate novel macroporous carbon prepared from a fibrous loofah sponge.