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Nanotechnology Spotlight

Behind the buzz and beyond the hype:
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Showing Spotlights 1241 - 1248 of 1781 in category (newest first):

 

Pilot toxicology study of intravenously injected carbon nanotubes

liver_histologyThe toxicity issues surrounding carbon nanotubes (CNTs) are highly relevant for two reasons: Firstly, as more and more products containing CNTs come to market, there is a chance that free CNTs get released during their life cycles, most likely during production or disposal, and find their way through the environment into the body. Secondly, and much more pertinent with regard to potential health risks, is the use of CNTs in biological and medical settings. CNTs interesting structural, chemical, electrical, and optical properties are explored by numerous research groups around the world with the goal of drastically improving performance and efficacy of biological detection, imaging, and therapy applications. In many of these envisaged applications, CNTs would be deliberately injected or implanted in the body. For instance, CNT-based intercellular molecular delivery vehicles have been developed for intracellular gene and drug delivery in vitro. What these CNTs do once inside the body and after they discharge their medical payloads is not well understood. Cell culture studies have shown evidence of cytotoxicity and oxidative stress induced by single-walled carbon nanotubes (SWCNTs), depending on whether and to what degree they are functionalized or oxidized. A new study at Stanford University tested non-covalently pegylated SWCNTs as a 'least toxic scenario', and oxidized, covalently functionalized nanotubes as a 'most toxic scenario' in a study on mice. It was found that SWCNTs injected intravenously into nude mice do not appear to have any significant toxicity during an observation period of four months following injection.

Posted: Apr 22nd, 2008

Silicon nanotubes could exceed their carbon counterparts in hydrogen storage efficiency

hydrogen_storage_silicon_nanotubesSafe, efficient and compact hydrogen storage is a major challenge in order to realize hydrogen powered transport. According to the U.S. Department of Energy's Freedom CAR program roadmap, the on-board hydrogen storage system should provide a gravimetric density of 6 wt% at room temperature to be considered for technological implementation. Currently, the storage of hydrogen in the absorbed form is considered as the most appropriate way to solve this problem. Research groups worldwide are seeking and experimenting with materials capable of absorbing and releasing large quantities of hydrogen easily, reliably, and safely. One candidate material that is being considered as a candidate for hydrogen storage media is single-walled carbon nanotubes. So far, carbon nanotubes have been unable to meet the DOE's hydrogen storage target. New theoretical work from China suggests that silicon nanotubes can store hydrogen more efficiently than their carbon nanotube counterparts. This raises the possibility that, after powering the micro-electronics revolution, silicon could also become a key material for the future hydrogen economy.

Posted: Apr 21st, 2008

Companies fail to apprise investors of potential nanotechnology risks

investingFollowing just two days after we wrote about the food industry's deafening silence on their nanotechnology research and development, the Investor Environmental Health Network today released a report that demonstrates that sectors affected by product toxicity risks are doing a poor job of informing shareholders of market risks they face due to toxic chemicals in their products. The report specifically addresses the situation for companies dealing with nanomaterials by noting that manufacturers are not disclosing the evidence of health risks of nanotechnology products, nor the lack of adequate product testing prior to their sales. An interesting observation is that some nanomaterial manufacturers are more open to communicating potential uncertainties than their customers. These customers of the nanomaterials are the manufacturers of an array of products from electronics to food and cosmetics - and they tend not to disclose the potential health and financial risks. IEHN's conclusion is that investors should be apprised of the state of the science by a company, instead of being misled to believe that the serious questions have been answered.

Posted: Apr 18th, 2008

Nanotechnology funding strategy in Germany shows a growing focus on sustainability aspects

GermanyThe European Union currently spends about 740 million Euros (roughly $1.2 billion) annually in public funding on nanotechnology research. This is almost on par with the U.S. National Nanotechnology Initiative (NNI) budget of $1.28 billion (2007). Almost 40% of public EU nanotechnology funding takes place in Germany and it is estimated that about half of the European companies active in nanotechnology are based in Germany, making the country the clear nanotechnology leader in Europe. Germany's strengths include a well structured research and development infrastructure and a high level of research in the various subfields of nanotechnology. The industrial base for utilizing the results of this research is also in place. About 700 companies are currently involved in the development, application, and sales and marketing of nanotechnological products. What sets public nanotechnology policy in Germany and other European countries apart from the U.S. is a more deliberate attempt to create, and evolve over time, an integrated approach in the development of nanotechnology research, trying to link sustainability questions and technology development.

Posted: Apr 17th, 2008

Food nanotechnology - how the industry is blowing it

twinkiesThe food industry is excited about the potential of nanotechnology. Food companies are very much involved in exploring and implementing nanotechnology applications in food processing, packaging and even growing - but you don't hear about it anymore. At least not from the companies. Large industrial food companies, no stranger to big and expensive media campaigns, have buried the subject of nanotechnology in their public relations graveyard. Take Kraft Foods for example. While it took the industry's nanotechnology lead when it established the Nanotek Consortium in 2000, it has since pulled back completely on the PR front. The Nanotek Consortium even was renamed the 'Interdisciplinary Network of Emerging Science and Technologies' (INEST), is now sponsored by Altria, and its single webpage makes no mention of food at all. Doing our regular check on the websites of large food companies we again found not a single reference to 'nanotechnology' or even 'nano'. The same is true for large food industry associations such as the Grocery Manufacturers/Food Products Association (GMA/FPA), which represents the world's leading food, beverage and consumer products companies. Faced with a complete nanotechnology communications blackout from the manufacturers, it is left to activist groups like Friends of the Earth to frame the discussion. These groups are trying to figure out what the food industry is up to and if there might be any risks involved that we should know about.

Posted: Apr 16th, 2008

Conductive and tunable transparent coatings made from monodisperse carbon nanotubes

carbon_nanotube_coatingsThere are several touch sensor technologies available to power touch screens like the ones you can find on your bank ATM, airport check-in kiosk or other self-service terminals. What they all have in common is that they are sensitive to human touch because their screens are coated with a special transparent thin film that act as a sensor. This sensor generally has an electrical current or signal going through it and touching the screen causes a voltage or signal change. Apart from touch screens, transparent conductive thin films are used in numerous products such as flat-panel displays, solar cells or as thermal barriers in energy-saving windows. Future applications will include flexible displays for e-papers, smart cards, 'heads-up' displays integrated into cockpit and car windows, and windows that can be used as a light source at night. All this has driven increased research activity in finding alternative novel transparent electrode materials with good stability, high transparency and excellent conductivity. Graphene is one good candidate and films based on carbon nanotubes have attracted significant attention recently as well. Researchers now have demonstrated the use of metallic nanotubes to make thin films that are semitransparent, highly conductive, flexible and come in a variety of colors.

Posted: Apr 15th, 2008

How falling spaghettis could lead to more complex nanotechnology self-assembly

spaghettiSelf-assembly and self-organization are terms used to describe processes in which a disordered system of pre-existing components forms an organized structure or pattern as a consequence of specific, local interactions among the components themselves, without external direction. Self-organizing processes are common throughout nature and involve components from the molecular (e.g. protein folding) to the planetary scale (e.g. weather systems) and even beyond (e.g. galaxies). Self-assembly has become an especially important concept in nanotechnology. As miniaturization reaches the nanoscale, conventional manufacturing technologies fail because it has not been possible (yet) to build machinery that assembles nanoscale components into functional devices. Until robotic assemblers capable of nanofabrication can be built, self-assembly - together with chemical synthesis - will be the necessary technology to develop for bottom-up fabrication. The key to using self-assembly as a controlled and directed fabrication process lies in designing the components that are required to self-assemble into desired patterns and functions. Self-assembly reflects information coded - as shape, surface properties, charge, polarizability, magnetic dipole, mass, etc. - in individual components; these characteristics determine the interactions among them.

Posted: Apr 14th, 2008

Nanotechnology solutions for Alzheimer's disease

alzheimer'sAlzheimer's disease (AD), a brain disorder named for German physician Alois Alzheimer who first described it in 1906, is a disease that destroys brain cells, causing problems with memory, thinking and behavior. Alzheimer's gets worse over time, and it is fatal. It is also the most common form of dementia. The latest estimate is that 26.6 million people were suffering from Alzheimer's disease worldwide in 2006, and this number will rise to 100 million by 2050 - 1 in 85 of the total population. The latest 2008 data for the US alone estimates that 5 million Americans have the disease, with an estimated increase to 11 to 16 million by 2050. Not only does Alzheimer's have no cure, even its cause is unknown (research has led to several theories that are still being investigated). The onset of AD is usually very slow and gradual and, since there is no test for it, there is no clear-cut line between normal age-related changes and warning signs. An absolute diagnosis of AD can only be determined during the examination of brain tissue, which is usually done during an autopsy. A recent report provides an overview of the promises that nanotechnology brings in research on diagnosis and therapy of AD.

Posted: Apr 11th, 2008