Nanotechnology has made great strides in biology and medicine in the past year. Here is a list of the top 10 developments in Nanodermatology in 2013, as compiled by the Nanodermatology Society. These topics will be the subject of multiple talks and two sessions at the American Academy of Dermatology Annual Meeting on March 21-25, 2014 in Denver. This, however, is just a sampling of the topics to be covered and world class speakers in medical nanotechnology.
Bi-stability is widely used in digital electronics devices to store binary data. It is the essential characteristic of the flip-flop, a circuit widely used in latches and some types of semiconductor memory. However, it is possible to store more data at the nanoscale with multi-stable memory functions. Researchers have now developed a multi-stable nonvolatile soft memory function by doping ferroelectric nanoparticles into liquid crystal matrices.
New work by an international team of researchers provides not only new insights into the chemical evolution of monodisperse nanoparticles from an atomic metal-dispersed precursor, but also a general route to obtain tunable nanoparticles as heterogeneous catalysts for chemical and material production. The team used an atomic metal-dispersed precursor of layered double hydroxides to synthesize high density, monodisperse metal nanoparticles. They then selected carbon nanotube growth as the probe reaction to evaluate the catalytic performance of the monodisperse metal nanoparticles catalysts.
Biological barriers - the skin, mucosal membranes, the blood-brain barrier and cell/nuclear membranes - seriously limit the delivery of drugs into the desired sites within the body, resulting in a low delivery efficacy, poor therapeutic efficacy, and high cost. Nanomedicine researchers have developed numerous biological, chemical, and physical strategies to overcome these barriers. This article highlights recent advanced physical approaches for transdermal and intracellular delivery.
Researchers have developed a low-cost generic batch process using a state-of-the-art CMOS process to transform conventional silicon electronics into flexible and transparent electronics while retaining its high-performance, ultra-large-scale-integration density and cost. This process relies on standard and cheap silicon (100) wafer and microfabrication techniques, which allows to fabricate high performing devices. Furthermore, it allows the recyclability of the wafer to produce several substrates with devices, making it economically attractive.
An artificial brain building program has created a process of circuit evolution similar to the human brain in an organic molecular layer. The research team has now finalized their human brain model and introduced the concept of a new class of computer which does not use any circuit or logic gate. The kind of CMOS based integrated chip that forms the core of existing supercomputers will not be used in this kind of computer. The team uses the term brain jelly to describe their purely organic computing architecture.
In order to fabricate entirely flexible electronic devices, the components that power them - such as batteries - not only need to be fully flexible as well but they have to be compatible with commercially available manufacturing technologies. This would require achieving a high degree of deformability without using elastomeric materials. Researchers have now demonstrated the fabrication of a highly deformable lithium-ion battery using standard electrodes and commercially standard packaging technologies.
Surface metrology and characterization is ever more critical for overall product performance in wide ranging applications across the semi-conductor, LED, data storage, medical and automotive industries. 3D optical microscopes are among the fastest and most accurate imaging systems on the market today, and are employed in these industries for rapid and precise process monitoring, product development, and research. However, there are instances where they have performance limitations and the benefits of scanning probe/atomic force microscopy provide a clear advantage.