A new study by Swedish researchers shows that gold nano spheres with a diameter of 7 nm, produced in a conventional laboratory surrounding, activate human antigen presenting dendritic cells (DCs) to induce proliferation of peripheral blood mononuclear cells (PBMC), mixed with either allergenic or autologous DCs. This effect was found to be due to endotoxin (lipopolysaccharide, LPS) contamination of the nanoparticles. When particles were produced in a controlled way eliminating endotoxin contamination, the activation of the DCs did not take place.
With the recent development in nanoscience and nanotechnology, a large variety of single-component nanomaterials (such as carbon nanotubes, nanoparticles, and quantum dots) and devices have been reported. There is now a pressing need to integrate multicomponent nanoscale entities into multifunctional systems and to connect these nano-systems to the micro/macro-world. This connection from the nano world to the macro world has been one of the long-standing problems in nanotechnology and still remains a big challenge. A novel approach of growing aligned carbon nanotubes (CNTs) around microsized carbon fibers should provide a useful platform technology for the development of various multidimensional and multifunctional nanomaterials and devices.
Researchers in Japan have synthesized novel silica fibers. Unlike any previously reported one-dimensional silica nano- and microstructures, the novel fibers display a triangular cross-section, which is not typical for amorphous materials. These prism-like silica fibers open up a new morphological type of silicon-based materials which may have highly promising potentials. They may be of significant interest for optoelectronic applications and the improvement of SnO2 chemical sensors and catalysts.
The fabrication of ultrafine structures beyond the limits of conventional lithography is a topic of tremendous importance and is expected to play a significant role in the realization of futuristic nanotechnology. It is also equally important to develop functional material systems of ultrafine dimensions in order to achieve this goal. An important step towards realization of nanodevices is self-organized nanopatterning of functional structures. A new technique, which might be called chemical lithography, enables the regular assembly of optically active nanoparticles on a silicon surface.
Researchers combined two different materials from nature, both of which have unique and important properties, into one material system via genetic engineering. By combining the features of silk with biosilica through the design, synthesis, and characterization of a novel family of chimeric proteins an innovative biomimetic nanocomposite was fabricated.
A new method based on the nanoscale Kirkendall effect was demonstrated to fabricate compound nanotubes. Through a spinel-forming solid-state reaction, high aspect-ratio core-shell ZnO-Al2O3 nanowires transform into monocrystalline ZnAl2O4 nanotubes.
Researchers at the University of Illinois at Urbana-Champaign have shown that, by employing small pieces of DNA molecules called aptamers, nanomaterials can be smart enough to assemble or disassemble only in the presence of programmable signals such as AND or OR, with controllable cooperativity.
In order to survive, biological systems need to form patterns and organize themselves. Scientists at the Max Planck Institute for Colloids and Interfaces (MPI-KG) in Potsdam, Germany, have now combined self-organization with chemical pattern formation. They demonstrated that oscillating reaction patterns like that of a Belousov-Zhabotinsky reaction can not only be generated in a one-phase system like in all previous examples but also in a two-phase system like liquid-solid.