Research related to molecular logic gates is a fast growing and very active area and molecular devices have become the new frontier in computing. Researchers now have designed and synthesized self-assembled DNA complexes that sense two environmental signals and produce a fluorescent outputs corresponding to the operation of all six Boolean logic gates AND, NAND, OR, NOR, XOR, and XNOR. This study could help improvements in the fields of molecular computation and intelligent drug delivery.
While the actual toxicity of Bisphenol A (BPA) is still debated, the direct measurement of BPA is difficult because of the weak response given by conventional electrochemical sensors, and current optical analysis methods are susceptible to the influence of interfering substances. A novel aptamer/graphene oxide FRET biosensor now provides a method for the rapid detection and risk assessment of BPA with high sensitivity and selectivity.
The commonly used separators in battery systems are porous polymer membranes, which separate the two electrodes while having little impact on the transportation of ions through the membrane. Polysulfides generated in a lithium-sulfur system can also diffuse freely through the membranes and react with a metal lithium anode, which results in the degradation of the battery's performance. If a novel, ion-selective but highly permeable separator can be developed, the shuttling of polysulfides and self-discharge would be effectively prevented, and both the energy density and power density of lithium-sulfur batteries could be significantly improved.
Novel materials designed and fabricated with the help of nanotechnologies offer the promise of radical technological development. Many of these will improve our quality of life, and develop our economies, but all will be measured against the overarching principle that we do not make some error, and harm ourselves and our environment by exposure to new forms of hazard. A publication explores recent developments in nanomaterials research, and possibilities for safe, practical and resource-efficient applications.
Supramolecular chemistry deals with molecular building-blocks that interact with each other in a dynamic manner, similar to what is seen in nature. Taking advantage of this, several 'smart' materials have been developed for biomedical applications by careful design of these building-blocks. These materials have especially interesting properties like self-healing and responsiveness to light and electricity. Researchers have now explored the possibility of developing a bacterial strain with the ability to interact dynamically with a popular supramolecular building-block.
A novel nanoparticle blood test detects an overall increase of human immunoglobulin G (IgG), including the tumor-specific autoantibodies, adsorbed to a gold nanoparticle surface. While this test may not be able to identify the specific type of cancer, it may potentially be able to detect early stage tumor-induced immune responses associated with a broad spectrum of cancer types, making this test potentially a universal screening test for cancer risk assessment.
Typically, in clinical formulations of Magnetic Resonance Imaging (MRI) contrast agents, gram quantities of Gd(III) are needed to achieve sufficiently high contrast for examination. That's why the research imaging community is interested in developing new formulations of contrast agents able to bridge the gap between high contrast imaging of contrast agents dosed at low concentrations.
In new work, researchers report a new class of gold nanoconjugates that exhibit exceptionally high relaxivities at both low and high field strengths.
In new work, researchers have utilized diffusion as an effective transport mechanism for DNA nanotechnology. These findings contribute a new aspect to be considered for the design of future DNA motors, molecular machines, and nanorobots as they provide a simple way to transport molecules over distances of potentially several 100 nm; which is much faster than when using conventional DNA walkers or motors, which make many small and slow steps.