A novel nanoparticle blood test detects an overall increase of human immunoglobulin G (IgG), including the tumor-specific autoantibodies, adsorbed to a gold nanoparticle surface. While this test may not be able to identify the specific type of cancer, it may potentially be able to detect early stage tumor-induced immune responses associated with a broad spectrum of cancer types, making this test potentially a universal screening test for cancer risk assessment.
Typically, in clinical formulations of Magnetic Resonance Imaging (MRI) contrast agents, gram quantities of Gd(III) are needed to achieve sufficiently high contrast for examination. That's why the research imaging community is interested in developing new formulations of contrast agents able to bridge the gap between high contrast imaging of contrast agents dosed at low concentrations.
In new work, researchers report a new class of gold nanoconjugates that exhibit exceptionally high relaxivities at both low and high field strengths.
In new work, researchers have utilized diffusion as an effective transport mechanism for DNA nanotechnology. These findings contribute a new aspect to be considered for the design of future DNA motors, molecular machines, and nanorobots as they provide a simple way to transport molecules over distances of potentially several 100 nm; which is much faster than when using conventional DNA walkers or motors, which make many small and slow steps.
Trying to develop chemical free disinfection techniques, researchers are currently exploring the effectiveness of a nanotechnology based intervention method for the inactivation of foodborne and spoilage microorganisms on fresh produce and on food production surfaces. This method utilizes Engineered Water Nanostructures (EWNS) generated by electrospraying of water. These EWNS are 25 nm in diameter; remain airborne in indoor conditions for hours; contain Reactive Oxygen Species (ROS); have very strong surface charge (on average 10 electrons per structure) and have the ability to interact and inactivate pathogens by destroying their membrane.
Researchers have developed a magnetic bead based sensor that combines magnetic separation (MS) and magnetic relaxation switch (MRS) for one-step detection of bacteria and viruses with high sensitivity and reproducibility. Compared to conventional assays for detection of bacteria and viruses, this novel MS-MRS assay is easy to operate without laborious pre-treatment, purification and can be adaptable to point-of-care tests easily.
Molybdenum disulfide's (MoS2) semiconducting ability, strong light-matter interaction and similarity to the carbon-based graphene makes it of interest to scientists as a viable alternative to graphene in the manufacture of electronics, particularly photoelectronics. In particular, MoS2 has excellent optical properties when deposited as a single, atom-thick layer - unlike graphene, it emits light when excited; albeit relatively poorly. In order to realize the potential of atomically thin MoS2 as a nanoscale active material in a light source, a considerable enhancement of its emission efficiency is necessary.
Historically, the approval of Doxil as the very first nanotherapeutic product in 1995 is generally regarded as the dawn of nanomedicine for human use. Although numerous products classified as nanomedicine products have indeed appeared over the past decade, such products have not exactly revolutionized treatment paradigms as envisaged earlier. In particular no molecular machine or nanorobot has yet entered clinical trials, although research in these areas is picking up pace.
Heat energy can be converted into electricity with very high efficiency through a temperature-induced electron flow process known as thermionic emission. Thermionic energy converters have been used with different heat sources, all of them requiring operation at high temperatures above 1500 K. A new study indicates that heat temperature can be lowered by an order of magnitude if using graphene as hot cathode. The findings indicate that a graphene-based cathode thermionic converter operating at 900 K could reach an efficiency of 45%.