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Post-Doctoral Fellow (m/f) for multi-sample data collection strategies (ID30) - PDID30-2B
The ESRF is a multinational research institute, situated in Grenoble, France and financed by 20 countries mostly European. It operates a powerful synchrotron X-ray source with some 30 beamlines (instruments) covering a wide range of scientific research in fields such as biology and medicine, chemistry, earth and environmental sciences, materials and surface science, and physics. The ESRF employs about 600 staff and is organized as a French société civile.
The ESRF is in the process of renewing its beamline portfolio. As part of this initiative the Structural Biology Group is now commissioning a new suite of state of the art beamlines for Macromolecular Crystallography (MX). The facility comprises three beamlines, one with micro-focus capability. You will play an important role in the developments of new data collection methods and software programmes, the running of the beamlines, and providing support to external users as local contact. Developments of your own research programme are encouraged.
Macromolecular crystallography presents particular problems in the planning, execution and completion of diffraction experiments. In those cases where several crystals of the same type are available, the result of the structure study can be substantially improved by using a multi-crystal data collection strategy. This approach can be applicable to the most difficult structural projects. To predict/perform the best diffraction data collection strategy in practice several scientific tasks have to be solved and software developments performed. For example, new algorithms for the characterization and ranking of macromolecular crystals accounting for crystal non-isomorphism, crystal diffraction quality and radiation damage effects need to be advanced or developed. New data collection schemes are also required for multi-crystal data collection.
We expect that the successful candidate will further develop this approach. To be able to undertake this task applicants must be comfortable with the appropriate experimental techniques and be able to demonstrate competence in computer programming.
You should hold a PhD in physics, computer science, (bio-) physics or closely related science with a strong interest in X-ray methods and instrumentation. Knowledge in advanced data analysis methods such as crystallography/scattering software would be of advantage. Basic experience with scientific programming methods would be very useful.
The working language of the ESRF is English. For further information on employment terms and conditions, please refer to http://www.esrf.fr/Jobs/Conditions. The ESRF is an equal opportunity employer and encourages applications from disabled persons.
Contract of 18 months, renewable for a further 6 to 18 month-period.Only candidates holding a Ph.D. obtained less than 3 years ago are eligible for Post-doctoral positions.