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Posted: November 16, 2009
New Digital Camera from Leica for Fluorescence Applications
(Nanowerk News) The detection and documentation of low light fluorescence
signals in live cell experiments is a particular challenge for digital
cameras. To meet this demand, Leica Microsystems adds the new Leica DFC345
FX to its portfolio of powerful digital cameras. In addition to combining
high sensitivity with high resolution, this new camera features a fast
image capture rate and a broad dynamic range, making it ideal for
multidimensional live cell observation under low light conditions.
Brilliant and detailed fluorescence photography
The two-megapixel CCD sensor (pixel size 4.4 µm) guarantees excellent
resolution of detail. The high dynamic range allows the acquisition of
multicolor images in one shot without time-consuming overlay. There is a
choice of 40 MHz pixel clock rate for fast image readout or a 20 MHz pixel
clock rate, ensuring low noise for top picture quality.
In low light conditions, photoelectric compo nents have to be cooled so
that the camera can produce noise-free pictures during long exposure times.
That’s why the Leica DFC345 FX is equipped with one-stage Peltier cooling
for effective suppression of background noise. This, combined with the high
resolution of detail, produces brilliant images rich in contrast – even for
weak fluorescence signals.
Fully integrated for versatile application potential
The FireWire-B interface allows simple and reliable transfer of data to the
computer without an additional power supply. The Leica DFC345 FX is fully
integrated into the software platforms of Leica Microsystems: the modular
Leica Application Suite (LAS) for simple fluorescence documentation and
image archiving, the user-friendly LAS AF for sophisticated, high speed
fluorescence applications and Leica MM AF (powered by MetaMorph) for
About Leica Microsystems
Leica Microsystems is a leading global designer and producer of innovative,
high-tech, precision optical systems for the analysis of microstructures.
It is one of the market leaders in each of its business areas: Microscopy,
Confocal Laser Scanning Microscopy with corresponding Imaging Systems,
Specimen Preparation, and Medical Equipment. The company manufactures a
broad range of products for numerous applications requiring microscopic
imaging, measurement, and analysis. It also offers system solutions for
life science including biotechnology and medicine, research and development
of raw materials, and industrial quality assurance. The company is
represented in over 100 countries with 11 manufacturing facilities in 8
countries, sales and service organizations in 19 countries and an
international network of dealers. The international management is
headquartered in Wetzlar, Germany.