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Posted: May 6, 2010

Interactive webinar on May 19th on Nanoparticle Tracking Analysis
(Nanowerk News) NanoSight invites registration for an interactive webinar on high-resolution nanoparticle characterization: “Nanoparticle Tracking Analysis – Complementing DLS for more Complex Dispersions”.
Hosted by NanoSight on Wednesday 19th May, first at 3pm UK time (10am US East Coast, 7am US West Coast) then repeated again, live, at 5pm UK time (12am US East Coast, 9am US West Coast), the subject will be the general characterization of nanoparticles in liquids.
For five years, NanoSight’s Nanoparticle Tracking Analysis (NTA) has developed against an established infrastructure of Dynamic Light Scattering (DLS). Whilst DLS (or Photon Correlation Spectroscopy, PCS) remains the accepted worldwide standard method for sub-micron particle sizing, NTA is increasingly recognized as having unique value with polydisperse systems. Here there is capability to view, size and count nano-scale particles on a particle-by-particle basis; to produce high-resolution particle size measurements which in turn are validated by real-time video images. Virtually all NTA users already had DLS available and added the NanoSight capability as an enhancement.
More than 200 users world-wide now benefit from NanoSight, with strength in applications in drug delivery, protein aggregation, toxicology of nanoparticles, virus counting and general characterization of complex suspensions.
The webinar will discuss:
  • Introduction to Ensemble and Single-Particle Sizing Techniques
  • Principles: Nanoparticle Tracking Analysis (NTA) and Dynamic Light Scattering (DLS, or Photon Correlation Spectroscopy, PCS)
  • Comparative Strengths and Limitations of NTA vs. DLS
  • Electron Microscopy and NTA in complement
  • NanoSight and Fluorescence operating modes
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    There will be presentations from two of NanoSight’s applications team. Dr Patrick Hole, Head of Development from the UK headquarters, will introduce the technology while his US colleague, Duncan Griffiths, will present the latest applications solutions.
    To learn more about nanoparticle characterization using Nanoparticle Tracking Analysis (NTA), please visit the company's website and register for the latest issue of NanoTrail, the company’s electronic newsletter.
    About NanoSight
    NanoSight Limited, of Salisbury, UK, provides unique nanoparticle characterization technology. “Nanoparticle Tracking Analysis” (NTA) detects and visualizes populations of nanoparticles in liquids down to 10nm (material dependent) and measures the size of each particle from direct observations of diffusion. This particle-by-particle methodology goes beyond traditional light scattering techniques such as Dynamic Light Scattering (DLS), or Photon Correlation Spectroscopy (PCS), in providing high-resolution particle size distributions. Additionally NanoSight measures concentration and validates all data with video of particles moving under Brownian motion.
    This characterization information is highly informative in understanding the more complex suspensions in biological systems, hence its wide application in development of drug delivery systems, viral vaccines, the study of toxicology of nanoparticles and their environmental fate and in biomarker detection. This real-time data also provides insight into the kinetics of protein aggregation and other time-dependent phenomena in a quantitative manner, at deeply sub-micron sizes.
    NanoSight has more than 250 systems installed worldwide with users including BASF, BP, GlaxoSmithKline, Novartis, 3M Corp., Roche, Solvay and Unilever together with many universities and research institutes. There are currently 100+ third party papers citing NanoSight results, with this reference base growing very rapidly as NanoSight consolidates its key contribution to nanoparticle characterization. For more information, visit www.nanosight.com.
    Source: NanoSight