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Posted: June 19, 2010

Kyoto University to Use SmartChip Real-Time PCR System to Identify and Compare Biomarkers to Advance Regenerative Tissue Research

(Nanowerk News) WaferGen Biosystems, Inc., a leading developer of state-of-the-art genetic analysis systems, has announced that scientists from Kyoto University will use the WaferGen SmartChip Real-Time PCR System to identify and compare biomarkers to advance their research to regenerate tissues such as bone, cartilage, and muscle, lost or reduced due to various causes. Kyoto University is one of ten early-access customers using the SmartChip platform to advance research results through the improved discovery and validation of biomarkers enabled by its high-throughput capability.
The researchers at Kyoto University are led by Professor Shinya Yamanaka, M.D., Ph.D., Director of Kyoto University's Center for iPS Cell Research and Application (CiRA), and a recent recipient of both the Imperial Prize as well as the Japan Academy Prize. They are using the SmartChip platform to better identify and compare biomarkers, important to the clarification of iPS cells.
"We are pleased that a university of the stature of Kyoto -- in existence for more than 100 years with more than 22,000 students today -- has chosen our SmartChip System as part of their ground-breaking research project," said Alnoor Shivji, chairman and CEO, WaferGen. "By providing both the discovery and validation of biomarkers on one platform, SmartChip enables more extensive gene analysis, a key component in the advancement of important new therapies such as regenerative treatments."
About WaferGen and the SmartChip Real-Time PCR System
WaferGen Biosystems, Inc. is a leader in the development, manufacture and sale of state-of-the-art systems for genetic analysis for the life science and pharmaceutical industries. The company currently offers its innovative fee-based service for gene-expression profiling, while continuing the early commercialization of its SmartChip Real-Time PCR System that is designed as the first whole genome, high-throughput gene expression real-time PCR platform for the gene expression and genotyping markets. The initial product on the SmartChip platform is the proprietary SmartChip Human Oncology Gene Panel that provides pathway based gene expression profiling for Oncology. In addition, the SmartChip Human microRNA Panel provides a comprehensive panel of over 800 microRNAs on a single SmartChip to enable discovery of disease specific microRNAs.
Combined with next-generation chemistry and optimized assays being developed by WaferGen under the guidance of David Gelfand, Ph.D., Chief Scientific Officer and one of the pioneers of PCR, this innovative system promises to deliver significant speed and cost advantages to researchers in the gene expression and genotyping markets.
Based on collaborations established with leading research institutions, WaferGen believes that the SmartChip Real-Time PCR System is positioned as the platform of choice for biomarker discovery and validation. The system will provide a number of key ease-of-use features including content-ready chips with gene panels optimized for microRNA, cancer, and whole genome. WaferGen believes the SmartChip Real-Time PCR System will be the first platform to combine the high-throughput capability and cost efficiencies of existing microarrays, with the sensitivity and accuracy of real-time PCR.
Source: WaferGen (press release)
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