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Posted: June 30, 2010

New Application Note Demonstrates Capabilities of NanoDrop 3300 for Cancer Research

(Nanowerk News) Thermo Fisher Scientific Inc. today introduced a new application note demonstrating how the Thermo Scientific NanoDrop 3300 enables cancer researchers to study DNA methylation events and polyamine induced DNA G-quadruplex formations by microvolume fluorometry. The NanoDrop™ 3300 allows researchers to perform fluorescence measurements simply, quickly and cost-effectively, making the instrument a valuable tool for cancer research and biomedical research applications. The new application note, entitled "Using the NanoDrop 3300 Fluorospectrometer for Cancer Research Applications", is available for download at www.nanodrop.com/3300apps.html.
This new application note reviews methods in the current literature where the NanoDrop 3300 enables scientists to investigate complex DNA structures within the field of cancer research. The application note provides an insight into the benefits of using fluorescence spectroscopy for proof of concept experimentation of DNA methylation detection assays, as well as DNA G-quadruplex analysis.
Fluorescence spectroscopy methodologies are also aiding the targeting of and delivery to cancer cells in vivo to correct defects, inhibit growth and induce apoptosis. In addition, the technique provides excellent sensitivity and specificity for researchers working in this field. The patented "cuvette-less" sample retention system employed by the NanoDrop 3300 enables fluorescent measurements using as little as one microlitre sample volume. The fluorospectrometer is also capable of analyzing multiple emission profiles from a single sample. In addition, the easy-to-use instrument has a small footprint, taking up minimal space in the laboratory.
Thermo Fisher Scientific is offering a free trial program for its instruments, including the NanoDrop 3300, in order to demonstrate the ease-of-use of its fluorescence technology. For a limited time, customers signing up for a trial will receive a free tee shirt by entering the promotion code "free tee". For more details, please visit www.nanodrop.com/TrialProgram.
Source: Thermo Fisher (press release)
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