A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.
Feb 5th, 2024
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Researchers have successfully coaxed a deadly pathogen to destroy itself from the inside out.
Jan 31st, 2024
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Directing microfluidic vortex flows to deposit recombinant E. coli cells as surface-adhered biofilms creates a new class of highly resilient, self-regenerative bioreactors for scalable biomaterial production.
Jan 31st, 2024
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Scientists developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Jan 31st, 2024
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Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
Jan 30th, 2024
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The majority of high-grade ovarian cancers involve mutations in the p53 tumor suppressor gene, crucial for DNA repair and cell regulation. Researchers now developed a synthetic mRNA that successfully produced functional p53 protein in laboratory conditions, showing promise in cancer cell lines.
Jan 24th, 2024
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Insights into homologous recombination (HR) promise new insights into cancer.
Jan 20th, 2024
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Researchers demonstrate how machine learning models can predict anti-inflammatory potential of polymers, enabling faster design of immunomodulatory biomaterials for medical implants.
Jan 20th, 2024
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The flexibility of a protein hinge plays a crucial role in the transfer of proteins in key cell processes.
Jan 17th, 2024
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Scientists devise method to speed up observations of high-throughput microbiological process.
Jan 15th, 2024
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Researchers presented a novel kind of cyclic peptide that, when light-irradiated, induces the formation or dissociation of nanotubes on demand.
Jan 3rd, 2024
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Novel corn protein scaffolds match standard tissue engineering materials in supporting human stem cells while enabling stable, customizable structures.
Dec 28th, 2023
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Scientists successfully harnessed artificial intelligence (AI) and deep-learning techniques to model atomic-level RNA 3D structures from primary RNA sequences. Called DRfold, this novel AI-based method improves the accuracy of RNA models by more than 70 percent, compared to traditional approaches.
Dec 21st, 2023
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A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes.
Dec 20th, 2023
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Scientists have created an intricate map of how the immune system functions, examining the molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.
Dec 14th, 2023
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Researchers report a computational method to predict the placement of proteins on AFM substrates based on electrostatic interactions.
Dec 13th, 2023
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A surprisingly simple expression for enzyme activity could help guide biotechnologists.
Dec 13th, 2023
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For the first time, it is possible to follow, step-by-step and with atomic resolution, what happens when the enzyme DNA photolyase repairs ultraviolet light-induced DNA damage.
Dec 4th, 2023
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