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Bioengineered human livers mimic natural development

An international team of researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ's developmental processes - greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells.

Posted: Jun 14th, 2017

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Chip captures individual cells in minuscule gels

The novel method keeps cells alive for multiple weeks, which makes it easier to study them. This makes it possible to, for example, test the action of new drugs and improve stem cell therapies with unparalleled control.

Posted: Jun 12th, 2017

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Bacteria used as factories to produce cancer drugs

Researchers have developed a method of producing P450 enzymes - used by plants to defend against predators and microbes - in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.

Posted: Jun 2nd, 2017

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Building better brains: A bioengineered upgrade for organoids

Scientists for the first time combine organoids with bioengineering. Using small microfilaments, they show improved tissue architecture that mimics human brain development more accurately and allows more targeted studies of brain development and its malfunctions.

Posted: May 31st, 2017

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Chemical coatings boss around bacteria, in the bugs' own language

Researchers have developed a way to place onto surfaces special coatings that chemically 'communicate' with bacteria, telling them what to do. The coatings, which could be useful in inhibiting or promoting bacterial growth as needed, possess this controlling power over bacteria because, in effect, they 'speak' the bug's own language.

Posted: May 30th, 2017

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Remembrance of things past - bacterial memory of gut inflammation

Researchers designed a powerful bacterial sensor with a stable gene circuit in a colonizing bacterial strain that can record gut inflammation for six months in mice. This study offers a solution to previous challenges associated with living diagnostics and may bring them closer to use in human patients.

Posted: May 29th, 2017

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