To improve the tumor-specific delivery of drug to tumors, a team of investigators has created a system of nanoparticles-within-a-nanoparticle that can be directed to and concentrated at the site of tumor using a magnetic field. Once at the tumor site, radiofrequency irradiation triggers drug release from the nanoparticles, bathing the tumors in drug and markedly reducing the growth of the tumors.
In attempt to develop a new therapeutic approach to treating peritoneal metastases, a research team at Boston University has developed a novel, drug-loaded polymeric nanoparticle that responds to the acidic pH inside tumor cells by expanding, releasing the anticancer agent paclitaxel slowly over a period of 24 hours.
Researchers have developed an in vitro method for assessing kinase activity in minute tissue samples from patients. The method involves an integrated microfluidics and imaging platform that can reproducibly measure kinase enzymatic activity from as few as 3,000 cells.
Gold nanoparticles have shown promise as miniature thermal scalpels that when irradiated with near-infrared light are capable of cooking tumors to death. Now, a team of investigators have found that gold nanoshells can be used to deliver just a little heat to breast tumor cells already treated with radiation, boosting the killing power of both therapies.
In 2007, Mehmet Toner and Daniel Haber and their collaborators at Massachusetts General Hospital and Harvard Medical School developed a microfluidic device capable of trapping rare circulating tumor cells (CTCs) from the blood of cancer patients. Since then, these investigators, working with Harvard Medical School colleague Shyamala Maheswaren, have shown that captured CTCs can be used to characterize tumors from patients with lung and prostate cancer.
A systematic study of phase changes in vanadium dioxide has solved a mystery that has puzzled scientists for decades, according to researchers at the Department of Energy's Oak Ridge National Laboratory.
ANEC, The European Consumer Voice in Standardisation and BEUC, the European Consumers' Organisation have published their reply to the European Commission public consultation on 'Proposal for a Commission definition of the term nanomaterial'.
So far, it has only been possible to image magnetic domains in two dimensions. Now, for the first time, Scientists at Helmholtz-Zentrum Berlin (HZB) have managed to create three-dimensional images of these domains deep within magnetic materials.
Easy-to-use nano-coating sprays with optical, electronic, biological properties, etc to cover surfaces! Teams from the Institut Charles Sadron, in collaboration with researchers from the Laboratoire de Biomateriaux et Ingenierie Tissulaire, have managed to improve and extend their technique of 'layer by layer' deposition.
FP7 is on course and is clearly making a significant contribution to European science and the development of the European Research Area. This is one of the key messages to emerge from the newly-published interim evaluation of the EU's Seventh Framework Programme (FP7).