Researchers have long known that certain peptides are capable of killing cells by inserting themselves into the cell membranes and disrupting normal membrane structure and function. Now, researchers have learned how to deliver these cytotoxic peptides to tumor cells using self-assembling nanofibers that can slip into cancer cells and allow the toxic peptides to do their job from inside the cell.
One of the promises of nanoparticles as delivery agents for cancer therapeutics is that they will attack tumors while sparing healthy tissue from the damage normally associated with today's anticancer therapies. That promise is closer to realization thanks to the results of a study in which tumor-bearing mice were treated with a single dose of radioactive gold nanoparticles.
A multi-institutional team of researchers and clinicians has published the first proof that a targeted nanoparticle can traffic into tumors, deliver double-stranded small interfering RNAs (siRNAs), and turn off the production of an important cancer protein using a mechanism known as RNA interference (RNAi).
The U.S. Commerce Department's National Institute of Standards and Technology (NIST) today announced a new competition for high-risk, high-reward research funding under the Technology Innovation Program (TIP). The new TIP competition offers cost-shared funding for innovative research on 'Manufacturing and Biomanufacturing: Materials Advances and Critical Processes'.
Many advances in energy, green chemistry, and human health must start with understanding the movement of electrons - making frame-by-frame movies of changing molecular bonds during chemical reactions, or the correlated behavior of electrons in complex solids. This will only be possible by freezing time within a few quintillionths of a second.
Researchers have evidenced a basic general mechanism describing how filamentous proteins assemble into ribbon like structures, the so-called Amyloid fibrils. Combining experiments and theory, they could explain how denatured milk proteins assemble into ribbon like structures composed of up to five filaments.
The EC NanoCom project has opened a web based industrial consultation to discover the key success factors in exploiting pre-competitive research. We are encouraging all nanotech companies to contribute to this study, which will help to influence the debate on the best mechanisms of commercialisation for nanotechnologies.
Weizmann Institute scientists have 'trained' an electronic system to be able to predict the pleasantness of novel odors, just like a human would perceive them - turning the popular notion that smell is completely personal and culture-specific on its head.
Scientists at the research neutron source FRM II of the Technische Universitaet Muenchen are taking a closer look at a high performance rechargeable battery for future hybrid locomotives. The study reveals the distribution of chemical substances within the battery during various states of charge.
An EU-funded research team from Austria's University of Innsbruck has invented a single atom laser which works on the same principle as a classic laser but also has quantum mechanical properties in its atom-photon interactions.