At the nanoscale, the properties of materials - mechanical, electrical, thermal, optical - often differ significantly from their bulk behavior. And while nanostructured and nanoengineered products are appearing in the marketplace, researchers are still trying to understand all aspects of materials properties of nanostructures and how they can be modified and controlled. Vacancies (also called Schottky defect) play a major role in the electrical and thermal transport as well as the mechanical behavior of materials. A vacancy is the simplest defect which can be created in a material - it corresponds to a lack of an atom in the lattice. New theoretical work calculates the size effect on the vacancy formation energy, the vacancy formation entropy and the vacancy concentration into nanomaterials through a top-down approach by using classical thermodynamics.
Chemotherapeutics generally show a delicate balance between maintaining a high enough dose to kill cancer cells while avoiding a dose so high that it causes severe toxic effects. One of the many promises of nanomedicine is a class of nanoscale drug delivery vehicles that can pinpoint cancer cells and deliver their tumor-killing payload right into cancer cells with high efficiency and no side effects. Based on a novel silica 'nanorattle' structure, a research team further extended their work to fabricate 'all-in-one' multifunctional gold nanoshells on silica nanorattles which combine remote-controlled photothermal therapy with chemotherapy. The results indicate that a combination of hyperthermia and chemotherapeutic agents is an encouraging approach to optimizing cancer therapy for the synergistic effects are greater than the two individual treatments alone.
Ranging from electronic gadgets to medical applications, many nanomaterial-based devices have appeared in the market. One of the most important issues for these devices is their reliability and life-time of operation. A vital factor behind these issues is the structural stability of the nano-device - debonding of the nanomaterial from the substrate material being the single largest contribution for device degradation. In order to improve bonding between nanomaterials and their substrate, it is essential to understand and quantify the bonding mechanisms. A new nano-scratch technique developed by researchers in the U.S. could serve as the basis for a reliable quantification technique for interpreting nanomaterial-substrate bond strength.
The toxicity issues surrounding carbon nanotubes (CNTs) are highly relevant for two reasons: Firstly, as more and more products containing CNTs come to market, there is a chance that free CNTs get released during their life cycles, most likely during production or disposal, and find their way through the environment into the body. Secondly, and much more pertinent with regard to potential health risks, is the use of CNTs in biological and medical settings. Some groups are using CNTs in research for vaccination as well as gene and cancer therapy. Here, the CNT applications are designed to interact directly with the immune system. Understanding the interplay between CNTs and immune proteins is therefore critical for both improving CNT applications in biology and medicine and avoiding potentially noxious immune responses.
Self-cleaning, water and dirt-repellent coatings have differing properties, functional principles and manufacturing processes. Self-cleaning of the 'Lotus Effect' type has its basis in chemical-physical principles - these surfaces are characterised by a special roughness and are strongly water-repellent; in the ideal case, rain is sufficient for cleaning. 'Easy-to-Clean' materials, in contrast, have a particularly flat surface, which is both water and dirt-repellent on the basis of chemical aspects. Although the amount of mechanical cleaning may be reduced, they are not self-cleaning. A third form of self-cleaning is that based on photo catalysis by nano titanium dioxide. On such surfaces UV radiation produces oxygen radicals that decompose organic material, which in turn is removed in the rain by a water film.
The OECD has just published a 111-page book on nanotechnology business that attempts to provide comprehensive, internationally comparable information on how different types of companies are affected by nanotechnology, how they use it in their innovative activities, how they acquire or develop relevant competences, as well as on the specific commercialization challenges they face. It also addresses the different role that new and small as well as larger companies will play in the commercialization of nanotechnology.The case studies provide qualitative insights into the commercialization of nanotechnology from the viewpoint of companies and thus complement studies which have relied primarily on publication and patent data or statistical surveys.
A key hurdle in realizing high-efficiency, cost-effective solar energy technology is the low efficiency of current power cells. In order to achieve maximum efficiency when converting solar power into electricity, ideally you need a solar panel that can absorb nearly every single photon of light - across the entire spectrum of sunlight and regardless of the sun's position in the sky. One way to achieve suppression of sunlight's reflection over a broad spectral range is by using nanotextured surfaces that form a graded transition of the refractive index from air to the substrate. Researchers in Finland have now demonstrated a scalable, high-throughput fabrication method for such non-reflecting nanostructured surfaces.
Nanotechnology researchers working on self-powered nanodevices - nanoscale systems that scavenge energy from their surrounding environment - have been experimenting with various power sources ranging from piezoelectric systems to sound. However, the most abundant energy available in biosystems is chemical and biochemical energy, such as glucose. Researchers in China have now reported a nanowire-based biofuel cell based on a single proton conductive polymer nanowire for converting chemical energy from biofluids into electricity, using glucose oxidase and laccase as catalyst. The output of this biofuel cell is sufficient to drive pH, glucose or photon sensors. The high output power, low cost and easy fabrication process, large-scale manufacturability, high 'on-chip' integrability and stability demonstrates its great potential for in vivo biosensing.