Posted: November 3, 2009

Malvern Sponsors Protein Aggregation Track at PepTalk 2010

(Nanowerk News) As well as presenting a technical paper and exhibiting from its range of Zetasizer light scattering solutions and Viscotek size exclusion chromatography systems, Malvern Instruments is sponsoring the ‘Protein Aggregation’ track at the next Cambridge Healthtech Institute PepTalk conference (January 11-15, 2010, San Diego, California).
‘Protein Aggregation: Understanding and Overcoming Analytic, Formulation, Manufacturing, and Regulatory Challenges’ extends over 13th and 14th January, and covers the latest trends and challenges with a focus on the understanding and control of protein aggregation.
On Thursday, 14 January during the ‘Mechanisms of Protein Instability, Aggregation, and Immunogenicity’ session, Malvern specialist, Dr Ulf Nobbmann, will present: ‘Predicting Stability of Concentrated Protein Formulations from Dilute Solution Properties’. He will examine the application of non-invasive light scattering techniques to predict formulation stability, using zeta potential, melting points, virial coefficients, and polydispersity measurements of the dilute solution.
On Tuesday, 12 January, Dr Kevin Mattison from Malvern will cover the ‘Characterization of sub-micron particulates using light scattering techniques’ as part of the short course - Characterization and Analysis of Particulates: Methods and Tools.
Conference participants will also have the opportunity to join Malvern Instruments’ protein specialists at the company’s exhibition booth (#15) to view and discuss the latest developments. On show will be Viscotek SEC systems and Malvern's Zetasizer family of light scattering solutions, including the world leading Zetasizer Nano, the new Zetasizer APS which automates measurements in industry standard 96- or 384-well plates, and the Zetasizer Micro V, dedicated to the size and molecular weight measurement of proteins. For more details visit and
About Malvern Instruments
Malvern Instruments provides a range of complementary materials characterization tools that deliver inter-related measurements reflecting the complexities of particulates and disperse systems, nanomaterials and macromolecules. Analytical instruments from Malvern are used in the characterization of a wide variety of materials, from industrial bulk powders to nanomaterials and delicate macromolecules. A broad portfolio of innovative technologies is combined with intelligent, user-friendly software. These systems deliver industrially relevant data enabling our customers to make the connection between micro (such as particle size) and macro (bulk) material properties (rheology) and chemical composition (chemical imaging).
Particle size, particle shape, zeta potential, molecular weight, chemical composition and rheological properties measurements are now joined by advanced chromatography solutions (GPC/SEC), extending Malvern’s technologies for protein molecular weight, size and aggregation measurements, and synthetic polymer molecular weight and distribution. The company’s laboratory, at-line, on-line and in-line solutions are proven in sectors as diverse as cement production and pharmaceutical drug discovery.
Headquartered in Malvern, UK, Malvern Instruments has subsidiary organizations in all major European markets, North America, China, Korea and Japan, a joint venture in India, a global distributor network and applications laboratories around the world.
Source: Malvern Instruments (press release)
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