Dolomite Leads the Way in Double Emulsion Research

(Nanowerk News) Dolomite, a world leader in microfluidic design and manufacture, has introduced the Mitos Double Chip Holder H. This new connector allows direct interfacing of two microfluidic chips with accurate micro-channel to micro-channel connection via a precision perfluoroelastomer gasket. Once aligned the connection provides minimal disruption to the fluid flow. In one application, this was demonstrated by the flow of a stream of 50 micron droplets from one chip to another, showing that standard chips can be used to generate double emulsions.
Designed for use with the Mitos Edge Connector 4-way, the Mitos Double Chip Holder H provides eight fluidic connections to 1.6mm OD tubing. Quick to connect and disconnect, the Mitos Double Chip Holder H operates over a wide temperature range (-15°C to 150°C) and pressure range (up to 10bar) and offers excellent chemical resistance allowing a broad range of solvents and chemicals to be used.
Mitos Double Chip Holder
Left: Mitos Double Chip Holder H with Gasket. Right: Mitos Double Chip Holder H with 2 Edge Connectors 4-way and 2 Droplet Junction Chips.
One key application of the Mitos Double Chip Holder H is the generation of double emulsions. Double emulsions have many important applications in nutrition, cosmetics and the pharmaceutical industry, for example allowing an active ingredient or a cell to be enclosed inside a protective outer shell. Creating a double emulsion requires both hydrophobic and hydrophilic surfaces in different parts of the system, which in a single device can be complex and expensive to achieve. The Mitos Double Chip Holder H provides a simple, time efficient and cost-effective solution. It allows direct coupling of a hydrophobic chip and a hydrophilic chip, enabling users to generate both water-oil-water and oil-water-oil droplets by simply switching the chips around.
For further information on Dolomite's complete portfolio of microfluidic products, including connectors/interconnects, pumps, valves and pressure/flow rate sensors as well as custom devices, please visit
The Dolomite Centre Limited
Established in 2005 as the world's first Microfluidic Application Centre, Dolomite focused on working with customers to turn their concepts for microfluidic applications into reality. Today, Dolomite is the world leader in solving microfluidic problems. With offices in the UK and US and distributors throughout the rest of the world, its clients range from universities developing leading-edge analytical equipment, to manufacturers of chemical, life sciences and clinical diagnostics systems.
Dolomite is pioneering the use of microfluidic devices for small-scale fluid control and analysis, enabling manufacturers to develop more compact, cost-effective and powerful instruments. By combining specialist glass, quartz and ceramic technologies with knowledge of high performance microfluidics, Dolomite is able to provide solutions for a broad range of application areas including environmental monitoring, clinical diagnostics, food and beverage, nuclear, agriculture, petrochemical, cosmetics, pharmaceuticals and chemicals. Furthermore Dolomite's in-house micro-fabrication facilities that include clean rooms and precision glass processing facilities allow to prototype and test all solutions rapidly which ensures a faster development cycle and reduces the time to market.
Source: Dolomite (press release)
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