Posted: January 7, 2008

Eugene Science CZ Sterols to Be Launched in New Japanese Cosmetic Product Line

(Nanowerk News) Eugene Science Inc. (OTC BB:EUSI.OB), a leader in the nutraceutical marketplace with its cholesterol lowering CholZero (CZ™) plant sterols, today announced it has agreed to sell its patented, nano-sized CZ™ plant sterols to Japan-based Kokumin Pharmaceuticals for launch in a new scientifically advanced cosmetic product line.
Kokumin Pharmaceuticals is an OEM manufacturer for cosmetic lines including internationally acclaimed Shiseido. Initially, Kokumin intends to market and distribute a moisturizing cream containing Eugene Science's nano processed plant sterols -- RIMOR -- to the Japanese market in the second quarter of 2008. Founded in 1935 and with annual sales of approximately $110 million, Osaka, Japan-based Kokumin is also one of the largest drugstore companies in Japan with over 200 retail stores known for a wide range of quality health and beauty products; (
Eugene Science is in discussion with other companies worldwide as it pursues the establishment of joint venture agreements to create, market and distribute cosmetic products containing the Company's unique CZ™ nano-sized sterols. Industry analysts recently reported that in 2006, the cosmetics and toiletries industry posted its highest growth rate since 2001; skin care, with sales of $60.1 billion in 2006, is the largest C&T sector.
"The cosmetic industry is enormous, and Eugene Science is developing a joint venture business model for introducing future cosmetic products containing our patented CZ™ worldwide," said Seung Kwon Noh, Chief Executive Officer, Eugene Science.
"Japan is a highly sophisticated marketplace for nutraceutical products, and the ideal country to launch what we believe to be the cosmetic industry's state-of-the-art in an anti-aging and beautifying moisture crème," Noh said. "Kokumin is a top tier and well respected cosmetic OEM manufacturer and retailer and is well positioned for successful launch into this market."
CZ™ Plant Sterols Benefits on Skin
While plant sterols have long been recognized for their health benefit on human skin, conventional sterols are not water-dispersible and can only be added to oil-based cosmetic products greatly limiting their utility. The unique water-dispersible feature of the Company's nano-sized CZ™ sterols, however, enables these sterols to be added to all cosmetic products.
The elemental structure of soy bean-based plant sterols resembles that of cholesterol, which is a key component in human skin composition. Until now, plant sterols were predominantly used as a functional food ingredient which suppresses the absorption of cholesterol in the small intestines -- but also serves as a key component to retain moisture in the skin and hair.
Plant sterols benefits include:
(1) Boost epidermal moisture retention internally
(2) Strengthen protective skin barrier with external stimulation
(3) Convenient topical delivery and absorption
Nano-size Plant Sterol Functional Mechanism
The nano sized particles allow the plant sterols to be applied through a topical delivery permeating the dermal layer dramatically more effectively than conventional sterols.
Similar to hair cell complex, intercellular lipid in the skin consists of ceramide, fatty acid, and cholesterol. Since plant sterol resembles cholesterol, supplying plant sterol to damaged stratum corneum or aged skin (lamellar structure is broken) can strengthen its barrier. In addition, compared to other sterols, the molecule size of Eugene Science nano-scale plant sterol (300nm) molecule enables it to easily pass through the epidermal layer and assist formation of lamellar structure internally. It also enables the skin to retain its moisture.
To be added to Eugene Science's investor lists, please contact Zachary Bryant at [email protected] or at 818-382-9718.
About Eugene Science, Inc.
Based in Seoul, Korea, Eugene Science is a global biotechnology company tackling ailments such as heart disease, obesity and diabetes through innovation in the nutraceutical field. Its first commercial heart disease product, CZ™, is a patented, nanoscience-based, water-dispersible functional food ingredient containing natural plant sterols that help maintain healthy cholesterol levels by inhibiting its absorption. CZ™ is available in capsule form, or as a food or beverage additive. These plant sterols are approved by the U.S. FDA for health claims related to cholesterol lowering efficacy. Please visit
Forward-Looking Statements: This document contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In addition, from time to time, Eugene Science, or its representatives, have made or may make forward-looking statements, orally or in writing. The words "estimate," "project," "potential," "intended," "expect," "anticipate," "believe" and similar expressions or words are intended to identify forward-looking statements. Such forward-looking statements may be included in, but are not limited to, various filings made by Eugene Science with the United States Securities and Exchange Commission (available at, press releases or oral statements made with the approval of an authorized executive officer of Eugene Science. Actual results could differ materially from those projected or suggested in any forward-looking statements as a result of a wide variety of factors and conditions. Reference is hereby made to Eugene Science's Annual Report on Form 10-KSB for the fiscal year ended December 31, 2006 for information regarding those factors and conditions. Among the important factors that could cause actual results to differ materially from management's projections, estimates and expectations include, but are not limited to: changing economic influences in the nutraceutical or cosmetic industry; dependence on key personnel; actions of third parties; the market for cosmetic or nutraceutical products containing Eugene Science's CZ™ ingredient; and availability of adequate financing. Readers are cautioned not to place undue reliance upon these forward-looking statements that speak only as of the date of this press release. Eugene Science undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events.
Source: Eugene Science, Inc.
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