(Nanowerk News) Oxford Optronix, the leading provider of advanced
research instrumentation for the clinical medicine and life science industries, today announces the
formal launch of HypoxyLab™ – the industry’s first benchtop, HEPA-filtered,
precision-controlled hypoxia workstation. HypoxyLab creates optimal, contamination-free conditions
for a wide variety of cell-based research fields, including cancer biology, radiation cell biology,
cardiovascular research, apoptosis, neurology, stem cell research, multidisciplinary drug
development and proteomics.
HypoxyLab is a unique, fully-featured and easy-to-use hypoxia workstation that accurately reproduces
physiological conditions for cell-based research. HypoxyLab provides a highly stable, localised
environment in which levels of oxygen, carbon dioxide, temperature and humidity are precisely controlled within a HEPA-filtered isolation work chamber.
Using the optional OxyLite™ module, HypoxyLab also uniquely offers support for direct oxygen
partial pressure (pO2) measurements from cell media or tissue using fibre-optic sensors. The
ergonomically-designed benchtop workstation maintains ultra-stable climatic conditions using
processor-controlled temperature and the latest nebulizer-based, humidifier technology –
delivering requisite levels of humidity whilst maintaining a Class 5 environment.
Precision concentrations of O2 and CO2 as well as chamber temperature and humidity are controlled
via a colour touch-screen display and delivered using unique, electronic gas flow controllers and
auto-calibrating, state-of-the-art sensors. The workstation displays real-time values of chamber O2,
CO2, Temperature and Humidity on the touch-screen and simultaneously records this information onto a
USB memory stick for off-line analysis. HypoxyLab’s highly optimised working volume ensures
ultra-rapid cell cycling and tissue response times, whilst precise oxygen profiling and cycling is
controlled via the intuitive graphical user interface. This allows researchers to easily create any
number of bespoke oxygen profiling patterns.
In tissue culture technology, there is a growing need for systems capable of creating precise and
reproducible mammalian cell environments – now recognised as vital for accurate analysis of
both cell metabolism and cell function. However, a significant proportion of cell biology research
is still performed in ‘traditional incubators’, in which cells are routinely exposed to
the oxygen values found in air – at least two or three times the value expected in normal
tissues – leading to cellular stress, significant physiological changes which influence
differentiation, growth factor signaling and other cellular processes including post-translational
By delivering a contamination-free environment that offers precise and continuous control of O2, CO2, temperature and humidity, Oxford Optronix’s new HypoxyLab workstation delivers a powerful new solution to research teams looking to accurately reproduce real-life physiological conditions in cell-based research.
Commenting on the launch, Andy Obeid PhD, CEO of Oxford Optronix said: “With the growing
industry-wide recognition of the need to create physiologically reproducible, low oxygen and hypoxic
environments for mammalian cells in the laboratory, we were determined to create a solution for our
customers that combines cost-effectiveness and a small form factor with unrivalled accuracy and
precision. Our new HypoxyLab is easy to use, economic to run and delivers the industry’s first
benchtop, HEPA-filtered hypoxia workstation with applicability for every cell-based research
About Oxford Optronix
Oxford Optronix is a global pioneer in the design, development and manufacture of sophisticated
instrumentation for clinical medicine and life science research.
Founded and managed by academic scientists and with a focus on continuous research and development,
Oxford Optronix is committed to making a positive contribution to both patient care and life science
research through the design and development of innovative medical devices and scientific instruments
for research professionals that set the gold-standard for quality.
Oxford Optronix’s product range includes opto-electronic bio-sensing devices for physiological
and tissue vitality monitoring, intelligent imaging systems for automated cell colony counting and
contamination-free hypoxia workstations for analysing cell metabolism and function.
With a track record of over 20 years’ success, Oxford Optronix’s team of highly
experienced scientists, engineers and technicians design, develop and manufacture its entire product
portfolio in-house, ensuring the very highest standards in quality and unparalleled customer
support. ( www.oxford-optronix.com)