Nanotechnology Products and Applications
Product: Verigene System
Product page: (external link)
Product Sector: Medical → Diagnostics → Contrast Agent
|Graphic of a gold nanoparticle functionalized with sequence-specific oligonucleotides.|
The Verigene System, is a benchtop molecular diagnostics workstation that utilizes patented gold nanoparticle technology to detect nucleic acid and protein targets of interest for a variety of applications. From the outset, the Verigene System was designed with users in mind. The goal: make molecular diagnostic testing simple, accessible, and flexible, but still provide the high sensitivity, accuracy, and rapid multiplex target detection required by these applications.
At the core of each Verigene System are two laboratory instruments, the Verigene® Reader and the Verigene Processor, and single-use laboratory consumables, the Verigene Test Cartridges.
Nanoparticles, as used in Nanosphere's Verigene System and tests, are typically 13-20 nanometers in diameter.
Depending upon the application, each nanoparticle is functionalized with either a defined number of oligonucleotides (i.e., short pieces of DNA or RNA with sequences complementary to target sequences of clinical interest) or a defined number of antibodies that are specific to a particular protein of interest (e.g., prostate-specific antigen [PSA], cardiac troponin I [cTnI]).