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10 nm silica particles with fluorescence dye covalently bound in the silica matrix are availbale with red fluorescence (excitation: 569 nm, emission: 585 nm). These particles have a hydrophilic surface with terminal Si-OH bonds. https://www.cd-bioparticles.com/p/DiagNano™-Red-Fluorescent-Silica-Nanoparticles-10-nm_258_262_293_3887.html