Research in the group focuses around two intertwined goals. These are first, to create complex materials with nanoscale periodicity using self-organization, and second, to produce new physical properties because of that nanoscale architecture.
Vaults are components of cells that were first described in 1986. Because the particle is abundant in all cells of higher organisms and highly conserved throughout evolution, it is likely that the function of the vault is important to life. This website is designed for the educated non-scientist. It summarizes the present state of knowlege of this fascinating particle.
The Western Institute of Nanoelectronics (WIN), a National Institute of Excellence, has been organized to build on the best interdisciplinary talents in the field of nanoelectronics in the world. WIN's mission is to explore and develop advanced research devices, circuits and nanosystems with performance beyond conventional scaled CMOS.
The Center for Environmental Implications of Nanotechnology (CEIN) explores the impact of libraries of engineered nanomaterials on a range of cellular lifeforms, organisms and plants in terrestrial, fresh water and sea water environments. By being able to predict which nanomaterial physicochemical properties are potentially hazardous, the CEIN will be able to provide advice on the safe design of engineered nanomaterials from an environmental perspective.
Research areas: Nano-to-microscale quantitative biophysics and bioengineering. Single-molecule interactions. Biomembrane mechanics. Cell adhesion and cellular shape and motion. Design and advancement of nano-to-micromechanical core technologies: Dynamic force spectroscopy. Dynamic tension spectroscopy. Biomembrane force probe. Optical tweezers. Automated micromanipulation and micropipette aspiration.
The Micro-Nano Innovations (MiNI) Laboratory, led by Dr. Tingrui Pan, is an incubator for exploratory interdisciplinary research bridging nanoengineering and biomedicine. They endeavor to develop novel micro-nanoengineered platforms for contemporary biological applications, to deliver innovative engineered solutions to pressing medical problems, and to educate next-generation bioengineers for future healthcare.
Seung-Wuk Lee's research group uses chemical and biological approaches to create precisely defined nanomaterials, to investigate complex phenomena at their interfaces, and to develop novel, biomimetic, functional materials. Specifically, they focus on bone and its basic building blocks to study the fundamental mechanisms of bone mineralization and resorption and to develop bioinspired functional materials and devices.