| Posted: Jan 16, 2015 |
Nanoparticles eliminate pathogen bacteria biofilm
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(Nanowerk News) Researchers from Kerman University of Medical Sciences studied the effect of nanoparticles on bacterial biofilms to find new methods for the treatment of bacteria infectious diseases ("Anti-biofilm activity of biogenic selenium nanoparticles and selenium dioxide against clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa, and Proteus mirabilis").
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Among the advantages of the application of the scientific achievement, mention can be made of reducing hospitalization time, antibiotics resistance time and therapeutic costs.
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Biofilm is a group of bacteria that is created in a polymeric extracellular such as proteins that stick to non-living surfaces. Bacteria cells existing in biofilm are stronger against antibiotics, and they have lower metabolism. Researchers tried in this research to produce and use nanoparticles that prevent or eliminate biofilms in bacteria compounds. The creation of these biofilms is one of the reasons for the death of millions of people in developing or even developed countries.
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According to the researchers, the use of nanoparticles can be considered a new approach among the various methods for the prevention of formation and elimination of bacteria biofilms. Therefore, the researchers produced selenium nanoparticles and studied its anti-biofilm effects.
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Previous reports suggested that selenium nanoparticles have antibacterial, anti-virus and antioxidant properties. However, the results of this research showed for the first time that selenium nanoparticles have noticeable anti-biofilm properties too. A clean biological, non-toxic and biocompatible process was used to produce the nanoparticles. A reducing microorganism was used to reduce selenium ions for the production of biogenic selenium nanoparticles at particle size range of 80-220 nm.
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