A nanotechnology-based platform for single molecule identification and digital quantification. The NanoString™ system uniquely barcodes individual target molecules, scans them, and delivers a literal inventory of target molecules in the biological sample.
Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, the company has created a powerful technology platform called single molecule, real-time, or SMRT, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform our understanding of biological systems by providing a window into these systems that has not previously been open for scientific study.
Quanterix Corporation is developing a novel platform for single molecule analysis that will bring an unprecedented level of sensitivity, precision, and assay robustness to clinical diagnostics, drug development, and life science research.
T2 Biosystems is creating a new generation of lab-quality diagnostic tools. Its technology is based on superparamagnetic nanoparticles. NanoDx particles have a superparamagnetic metal core surrounded by a polymer layer decorated by multiple analyte-specific binding agents. This nanoparticle platform can be used with a variety of binding agents such as antibodies, nucleic acids and small molecules.
The company sells nanowire sensing devices for molecular diagnostics - real-time, continuous flow and label free over 5 logs dynamic range to 10s of fm/mL sensitivity of proteins, nucleic acid and viruses. Virus LOD is single viruses.