(Nanowerk News) Researchers are developing computational models to predict the behaviour of nanomaterials in biological systems. Such predictions will allow researchers to streamline and prioritise the toxicological testing of nanomaterials.
Although QSAR methodologies are well-known and have been extensively used in the areas of drug discovery and chemical toxicology, their application to nanomaterials is still in its infancy. Burello & Worth's recent contribution in this domain is the JRC study ("A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles") published in July 2010, proposing a theoretical framework for predicting the oxidative stress potential of oxide nanoparticles.
Source: European Commission, Joint Research Centre