Researchers from Purdue University has reproduced portions of the female breast in a tiny slide-sized model dubbed "breast on-a-chip" that will be used to test nanoparticle-based approaches for the detection and treatment of breast cancer. The model mimics the branching mammary duct system, where most breast cancers begin, and will serve as an "engineered organ" to study the use of nanoparticles to detect and target tumor cells within the ducts.
By replacing a chemical group in the macromolecule, researchers have found a way to bypass RNase and create stable three-dimensional configurations of RNA, greatly expanding the possibilities for RNA in nanotechnology.
Rice University bioengineers and physician-scientists at Baylor College of Medicine and Texas Children's Hospital have successfully destroyed tumors of human brain cancer cells in the first animal tests of a minimally invasive treatment that zaps glioma tumors with heat. The tests involved nanoshells, light-activated nanoparticles that are designed to destroy tumors with heat and avoid the unwanted side effects of drug and radiation therapies.
A paper published recently in the journal Nanomedicine could provide the foundation for a new ovarian cancer treatment option, one that would use an outside-the-body filtration device to remove a large portion of the free-floating cancer cells that often create secondary tumors.
Driven by scientific progress and economic stimulus, medical diagnostics will move to a stage in which straightforward medical diagnoses are independent of physician visits and large centralized laboratories. The future of basic diagnostic medicine will lie in the hands of private individuals. Researchers have taken significant strides towards achieving this goal by developing an autoassembly assay for disease biomarker detection which obviates the need for washing steps and is run on a handheld sensing platform.
A large team of researchers from the Massachusetts Institute of Technology, Massachusetts General Hospital, and Harvard Medical School have developed multilayered, or multistage, nanoparticles that partially dissolve once they accumulate around tumors, leaving behind a payload of nanoparticles a mere one-tenth the size of the original delivery vehicle.
Researchers at the Massachusetts Institute of Technology (MIT) and Brigham and Women's Hospital have shown that they can deliver the cancer drug cisplatin much more effectively and safely in a form that has been encapsulated in a nanoparticle targeted to prostate tumor cells.
Researchers at Northwestern University's Institute for Catalysis in Energy Processing have discovered a new strategy for fabricating metal nanoparticles in catalysts that promises to enhance the selectivity and yield for a wide range of structure-sensitive catalytic reactions.
A prototype implantable eye pressure monitor for glaucoma patients is believed to contain the first complete millimeter-scale computing system. And a compact radio that needs no tuning to find the right frequency could be a key enabler to organizing millimeter-scale systems into wireless sensor networks. These networks could one day track pollution, monitor structural integrity, perform surveillance, or make virtually any object smart and trackable.
Researchers from North Carolina State University have developed a faster, easier way to create microelectrodes, for use in microfluidic devices, by using liquid metal. Microfluidic devices manipulate small amounts of fluid and have a wide variety of applications, from testing minute blood samples to performing advanced chemical research.
Photons in the microwave frequency range are important in quantum research - for quantum information processors, for example. Now, for the first time, researchers have achieved the controlled production of single photons in the microwave region and successfully detected them with highly sensitive measuring instruments - although they are 100,000 times weaker than the photons emitted by an electric light bulb.
The World Gold Council today announced that it is to play a pivotal role in the transition of new gold-based innovations from 'lab' to 'market'. There has been an explosion of interest in the use of gold in science and technology, mainly driven by the emergence of nanotechnology, yet breakthroughs in research are slow to achieve commercial success due to lack of further targeted investment and support.
Working with a special kind of polymer called a block copolymer, a UB research team has synthesized a new kind of nanomembrane containing pores about 55 nanometers in diameter -- large enough for water to slip through easily, but too small for bacteria.