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Posted: May 26, 2017
A nanomedicine approach against multidrug-resistant bacteria
(Nanowerk News) Several antibacterial nanomaterials (such as silver, zinc oxide, titanium dioxide, tellurium, and copper oxide nanoparticles) can be effective against multidrug-resistant (MDR) bacteria-caused wound infection.
These nanomaterials, however, can be cytotoxic or hemolytic. That's why researchers are exploring wound dressing materials that can protect against MDR bacteria.
This kind of AuNP shows effective antimicrobial activity and outstanding biosecurity. The electrospun nanofibrous mats incorporating the antibacterial AuNPs show adequate wound healing property in vivo against bacterial wound infection.
This work can broaden antibiotic screening space and the applications of AuNPs, which may provide an option against MDR bacterial infections. The homogeneous electrospun nanofibers are promising for use in clinical treatment of wound infection.