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Posted: Oct 15, 2014
European Commission opens the gate towards the implementation of Nanomedicine Translation Hub
(Nanowerk News) A major step in implementing the ETPN Translation Hub has been reached, with three European projects entering the finalisation stage of their EU Grant Agreements. The project ENATRANS is for networking of SMEs in the nano-biomedical sector and supporting the SMEs with getting their products from the laboratory phase to the clinical applications. The projects 'NANOFACTURING' and 'NANOPILOT' will establish pilot lines to scale-up the production of novel nanopharmaceuticals from the lab-scale to the quantities needed for clinical testing. This announcement took place during the ETPN Annual Event 2014 in San Sebastian, Spain.
The ENATRANS project (Enabling NAnomedicine TRANSlation) will ensure the global coherence of the Translation Hub and build a functioning supply chain of nanomedicine projects mainly ran by SMEs and ready to meet industrial and clinical needs. A Translational Advisory Board (TAB) will serve as the cornerstone to provide specific advice, guidance and recommendations to all nanomedicine actors dealing with translation issues and in need of assistance in specific areas of expertise.
Coordinator: ETPN Secretariat c/o VDI/VDE-IT (DE). Consortium: Nanobiotix (FR), CEA-Leti (FR), Bioanalytik Muenster e.V. (DE), Tel-Aviv University (IL), Fondazione Don Carlo Gnocchi ONLUS (IT), and TecMinho (PT).
Duration: 3 years – Budget: €2 Mio.
The NanoFacturing project has two principal objectives. Firstly to scale up an existing Good Manufacturing Practice (GMP) pilot line to a medium scale sustainable manufacturing process for solid core nanopharmaceuticals with a primary focus on glycan-coated gold nanoparticles. The process will also support consortium partners’ clinical programs such as IFOM’s antiviral Dengue fever NP and other EU-wide nanomedicine programs. Secondly to create a large scale process platform that would serve as the basis for GMP compliant industrial manufacture and that will be available as a model for other European companies wishing to develop their own products.
Coordinator: Midatech Biogune (ES). Consortium: Centre for Process Innovation Limited (UK), Prochimia Surfaces SP.Z.O.O (PL), Galchimia S.A (ES), the University College Dublin and the National University of Ireland (IE), Applus S.A. LGAI Technological Center, S.A (ES), IFOM, Fondazione Istituto FIRC di Oncologia Molecolare (IT), and Ecole Polytechnique Federale de Lausanne (CH).
Duration: 4 years – Budget: €8 Mio.
The NanoPilot project will build a pilot line for the production of polymer based nanopharmaceuticals in compliance with GMP. The size of the plant aims to be very small, with three systems to be produced at the end of the project. Continuous flow microreactors will be employed for two of the nanopharmaceuticals to be manufactured.
Coordinator: the Research Centre IK4-CIDETEC (ES). Consortium : A Research Institute - UT2A-ADERA (FR); two Universities - National University of Ireland, Galway (IE) and Universidad de Santiago de Compostela (ES) ; two industries - Sylentis (ES) and Chemtrix (NL) ; and three SMEs - iX-Factory (DE), Mejoran (ES) and Spinverse (FI).
Duration: 4 years – Budget: €6.28 Mio.
Patrick Boisseau, chairman of the ETPN, added: “We are very proud to announce such important news during the ETPN Annual Event 2014. The success of the EU calls – 18 proposals have been received for pilot lines for upscaling the manufacturing of nanopharmaceuticals - shows the adequacy of ETPN recommendations with real SMEs needs. We also look forward for the perspectives on a nano-characterisation infrastructure, another major pillar of the Translation Hub asked by European nanomedicine actors. The ETPN is excited to work hand in hand with the different coordinators for a global coherence of actions and a more efficient European value chain in nanomedicine.”
The ETPN Annual Event 2014 is taking place in San Sebastian (Spain) from October 15th to 16th, kindly co-organised by the nanoBasque Agency (SPRI) and hosted by CIC nanoGUNE, the Basque nanoscience cooperative research centre.