An international team of scientists has succeeded in designing the world's first triply twisted molecule. Because of their peculiar quantum mechanical properties these structures are interesting for applications in molecular electronics and optoelectronics.
Using molecules of DNA like an architectural scaffold, scientists have developed a 3-D artificial enzyme cascade that mimics an important biochemical pathway that could prove important for future biomedical and energy applications.
Through a combination of high-resolution cryo-electron microscopy (cryo-EM) and new methodology for image analysis and structure interpretation, researchers have produced images of microtubule assembly and disassembly at the unprecedented resolution of 5 angstroms. Among other insights, these observations provide the first explanation of Taxol's success as a cancer chemotherapy agent.