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Protein 'passport' helps nanoparticles get past immune system

The body's immune system exists to identify and destroy foreign objects, whether they are bacteria, viruses, flecks of dirt, or splinters. Unfortunately, nanoparticles designed to deliver drugs, and implanted devices, like pacemakers or artificial joints, are just as foreign and subject to the same response. Now, however, a team of researchers has identified a 'passport' for such therapeutic devices, enabling them to get past the body's security system.

May 17th, 2013

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Nanoparticle harnesses powerful radiation therapy for cancer

Researchers at the University of Missouri have demonstrated the ability to create a multi-layered harness nanoparticle that can safely encapsulate powerful alpha-emitting radioisotopes and target tumors. The resulting nanoparticles not only offer the possibility of delivering tumor-killing alpha emitters to tumors, but also sparing healthy tissue from radiation damage.

May 17th, 2013

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Microneedle-delivered nanoparticles boost anti-tumor vaccines

In the quest to develop anti-cancer vaccines that would stimulate the body to destroy tumors and keep them from recurring, researchers continually run into the same problem - the immune-stimulating proteins, known as antigens, are not interacting effectively with the key immune system cells that trigger long-lasting immune responses. Now, using a novel administration system and polymer nanoparticles, a team of investigators led by Adrien Kissenpfennig of Queen's University Belfast has shown that they can deliver anticancer antigens to dendritic cells and trigger an effective immune system response against melanoma tumors.

May 17th, 2013

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New nanopore sensor simplifies analysis of methylated DNA

DNA methylation, the addition of a methyl group to specific locations on a DNA strand, plays a critical role in determining which genes are active in a cell at any given time. It plays an important role in embryonic development, cell growth and reproduction, and many diseases, including cancer. Now, researchers collaborating at the Mayo Clinic and the University of Illinois in Urbana-Champaign have developed a novel single molecule test for detecting DNA methylation that should greatly simplify and advance the study of this important genomic process.

May 17th, 2013

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European nanoelectronics program drives the future of power electronics

LAST POWER, the European Union-sponsored program aimed at developing a cost-effective and reliable technology for power electronics, today announced its three-year program achievements that place Europe at the forefront of research and the commercialization of energy-efficient devices for industrial and automotive applications, consumer electronics, renewable-energy conversion systems, and telecommunications.

May 17th, 2013

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'Folding materials' researchers earn NSF grant

Cornell researchers Jenny Sabin, assistant professor of architecture, and Dan Luo, professor of biological and environmental engineering, are among the lead investigators on a new research project to produce 'buildable, bendable and biological materials' for a wide range of applications.

May 17th, 2013

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Advancements and developments of solid-state nanopores sensors

Researchers at National Nanotechnology Center (NANOTEC) in Bangkok and Imperial College London (Department of Chemistry) in United Kingdom have studied the advancements of solid-state nanopores for the purpose of highlighting selected developments that will benefit scientists.

May 17th, 2013

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The first fully integrated artificial photosynthesis nanosystem

Scientists with the Lawrence Berkeley National Laboratory (Berkeley Lab) have reported the first fully integrated nanosystem for artificial photosynthesis. While 'artificial leaf' is the popular term for such a system, the key to this success was an 'artificial forest'.

May 16th, 2013

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