Singapore's Institute of Bioengineering and Nanotechnology (IBN) has invented a unique user-friendly gel that can liquefy on demand, with the potential to revolutionize three-dimensional (3D) cell culture for medical research.
Bacterial nanoinjectors transport proteins across three membranes: the inner and outer bacterial membranes plus the host cell membrane. Nanoinjectors essentially connect the bacterial cell contents with the host cell's and form a conduit for delivering bacterial effector proteins into the host. Once inside, these proteins reprogram the host's cellular functions to promote survival, growth, and bacterial propagation
Until recently, scientists couldn't create the nanoparticles without producing synthetic chemicals that had negative impacts on the environment. A new method, created by a University of Missouri research team, not only eliminates any negative environmental impact, but also has resulted in national and international recognition for the lead scientist.
Researchers at the University of Illinois at Urbana-Champaign have developed a new process for making nanoparticles that relies on paclitaxel itself to serve as the initiator that triggers polymer synthesis. The result is not only a stable nanoparticle formulation of paclitaxel but also one with very high and very controlled amounts of drug being incorporated in the nanoparticle.
Using a combination of polymers that respond to temperature, a research team at the University of Utah has developed a multifunctional nanoparticle that can image tumors using ultrasound and simultaneously deliver cell-damaging energy and anticancer drugs to those tumors. In addition, these nanoparticles appear to act specifically on tumors and not on healthy tissue.
In an effort to overcome the drug resistance that often occurs in cancer, a team of investigators has developed a nanoparticle made of a blend of polymers that first releases a powerful anticancer drug and then delivers an agent that tricks a drug-resistant cell into committing suicide. Now, tests in mice with human breast cancer have shown that these blended nanoparticles are effective in maintaining high levels of both drugs in the vicinity of tumors.
Researchers at the Center for Cancer Nanotechnology Excellence Focused on Therapy Response (CCNE-TR), based at Stanford University, have found a new way to target cancer cells while leaving healthy cells untouched.
New research describes the development of a perfluorinated nanoparticle loaded with gadolinium ions, which boost magnetic resonance imaging (MRI) signals, and then coating this nanoparticle with a peptide that targets new blood vessels.
By combining a magnetic nanoparticle, a fluorescent quantum dot, and an anticancer drug within a lipid-based nanoparticle, a multi-institutional research team headed by members of the National Cancer Institute?s (NCI) Alliance for Nanotechnology in Cancer has created a single agent that can image and treat tumors.
Rice University has established a National Corrosion Center where researchers will develop better technology for preventing corrosion - a problem that is estimated to cost $276 billion a year in the U.S.
The first concrete result of the work ISO launched in 2005 to develop standards to support the innovative field of nanotechnologies comes with the publication of ISO/TS 27687:2008, which provides terms and definitions related to particles in the field of nanotechnologies.
In a new study, physicists at the University of Toronto have invented a simple structure called a meta-screen, designed to focus light into tiny spots smaller than the wavelength of the photons in use.
Physicists at Osaka University in Japan used colored light to selectively manipulate different types of carbon nanotubes. They found that some of nanotubes displayed a tendency to cluster at the focal area of a focused laser beam.
A new imaging method for breast cancer has been developed by a team of scientists from Penn State Milton S. Hershey Medical Center and Penn State College of Medicine and the departments of Materials Science and Engineering and Physics at Penn State. Their researche utilizes encapsulated fluorescent molecules in calcium phosphate nanoparticles and non-toxic near infrared imaging.
An international team of scientists from RIKEN at Brookhaven National Laboratory and elsewhere in the USA, Japan and the UK are testing the Standard Model - the foundation of high-energy physics that unifies three of the four known forces found in nature - by calculating a well-known nuclear decay process.