As a means of helping researchers develop nanoparticle-based formulations of water-insoluble drugs, investigators have conducted a systematic study to quantify some of the key parameters involved in forming stable nanoparticles containing maximum levels of water-insoluble drug molecules.
Using temperature-sensitive, lipid- and polymer-based nanoparticles with a polymer coating, researchers have created an anticancer drug delivery vehicle that may provide a significant boost to the therapeutic efficacy of anticancer agents, particularly when used in conjunction with hyperthermia.
In a powerful demonstration of how to build a multifunctional, smart nanoscale drug delivery system, researchers have created a drug-loaded nanocontainer that targets specific cells and releases its payload when receiving a specific physiological signal.
The October issue of nanoRISK looks at the emergence of nanotoxicology; nanotechnology applications in architecture; the flip side of using carbon nanomaterials for environmental pollutant removal; and numerous briefs on papers, initiatives, upcoming events and new literature.
Researchers have developed a 55,000-pen, two-dimensional array that allows them to simultaneously create 55,000 identical patterns drawn with tiny dots of molecular ink on substrates of gold or glass. Each structure is only a single molecule tall.
Investigators developing an inhalable nanoparticle for treating lung cancer have shown that a surface molecule found on malignant lung cells can serve as an effective target for improving drug delivery.