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From blue pill to blue light

Researchers have developed a novel biotechnological solution for erectile dysfunction: a gene therapy that triggers reliable erections.

Posted: Mar 23rd, 2015

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Improved understanding of protein complex offers insight into DNA replication initiation mechanism basics

A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.

Posted: Mar 18th, 2015

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Researchers establish proof of concept for an entirely new approach to drug design

Exploring the fundamental mechanism by which a cell-surface receptor transmits its signal, researchers have established proof of concept for an entirely new approach to drug design. They report that a class of synthetic molecules known as diabodies can, from outside the cell, latch onto a target receptor and manipulate it in such a manner as to induce distinct and varying effects within cells and tissues.

Posted: Mar 16th, 2015

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