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Bioengineered livers mimic natural development
Scientists discover that three-dimensional liver buds grown in a dish from stem cells mimic the molecular signatures observed during the natural development of human liver.
Posted: Sep 1st, 2017
Read moreKey factor identified in gene silencing
Ubiquitinated histone gene silencing is vital in embryo development and goes awry in some cancers.
Posted: Aug 31st, 2017
Read morePlacenta-on-a-chip: Microsensor simulates malaria in the womb to develop treatments
By combining microbiology with engineering technologies, researchers are developing a first-of-its-kind 3D model that uses a single microfluidic sensing chip to study the complicated processes that take place in malaria-infected placenta as well as other placenta-related diseases and pathologies.
Posted: Aug 29th, 2017
Read moreNew open-source software for analyzing intact proteins
'Informed-Proteomics' eases top-down proteomics.
Posted: Aug 29th, 2017
Read moreLEGO-like proteins revealed
LEGO-like assemblies should have formed relatively frequently during evolution, according to scientists.
Posted: Aug 28th, 2017
Read moreSingle-nucleus RNA sequencing, droplet by droplet
DroNc-Seq - a technology that merges single-nucleus RNA sequencing with microfluidics - brings new scale to gene expression studies in complex tissues.
Posted: Aug 28th, 2017
Read moreCLAMP's dual duties may make it model for studies of protein function in context
New research on a crucial protein in fruit flies provides a clear model for a fundamental question in biology that's significant for drug development in particular: What influences the exact same protein to coordinate a vital molecular process on one chromosome but an entirely different one on another chromosome?
Posted: Aug 28th, 2017
Read moreResearchers unlock regenerative potential of cells in the mouse retina
Researchers use a clue from zebrafish to discover the cues that reprogram Muller glia into retinal neurons.
Posted: Aug 28th, 2017
Read moreE. coli tripeptide production model reveals surprising complexity
The incredible complexity of a single-celled organism is revealed by a computer model of protein production.
Posted: Aug 25th, 2017
Read moreThe science of fluoride flipping
A new imaging technique helps researchers study tiny, time-sensitive biological processes - the crucial underpinnings of human health and disease.
Posted: Aug 23rd, 2017
Read moreDNA sensor system developed for specific and sensitive measurement of cancer-relevant enzyme activity
The development of DNA sensor systems is of great importance for advances in medical science. Now another piece of the puzzle for the development of personalized medicine has been found with the results of a highly sensitive monitoring of cancer-related topoisomerase II enzymes.
Posted: Aug 23rd, 2017
Read moreSpinning plant waste into carbon fiber for cars, planes
Researchers report transforming lignin into carbon fiber to produce a lower-cost material strong enough to build car or aircraft parts.
Posted: Aug 23rd, 2017
Read moreTreating arthritis with algae
When chemically modified, this 'alginate' reduces oxidative stress, has an anti-inflammatory effect in cell culture tests and suppresses the immune reaction against cartilage cells, thereby combating the causes of arthritis.
Posted: Aug 23rd, 2017
Read moreQuantum ruler for biomolecules
Physicists measure molecular electronic properties of vitamins.
Posted: Aug 22nd, 2017
Read moreA tougher dental restoration composite
Scientists developed a new dental restoration composite that proves more durable than the conventional material.
Posted: Aug 22nd, 2017
Read moreBiophysics explains how immune cells kill bacteria
A new data analysis technique, moving subtrajectory analysis, defines the dynamics and kinetics of key molecules in the immune response to an infection. These biophysical descriptions are expected to clarify the TCR microcluster, an essential assembly for a T cell to initiate its attack on a pathogen.
Posted: Aug 21st, 2017
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