Biologists have developed a method for rapidly screening hundreds of thousands of potential drugs for fighting infections, an innovation that holds promise for combating the growing scourge of antibiotic-resistant bacteria. The method involves engineering bacteria to produce and test molecules that are potentially toxic to themselves.
Scientists have developed so-called secondary nanobodies that can replace the most-used antibodies and may drastically reduce the number of animals in antibody production. This is possible because the secondary nanobodies can be produced in large scale by bacteria.
Researchers successfully constructed a first-of-its-kind chemical oscillator that uses DNA components. DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have visualized the atomic structures of the Cpf1 and Cas9 proteins to analyse each of their properties and peculiarities that make them ideal for different applications in gene modification.