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Pathway for membrane building blocks

Biomembranes consist of a mosaic of individual, densely packed lipid molecules. These molecules are formed inside the cells. But how do these building blocks move to the correct part of the membrane? Researchers from Technische Universit�t M�nchen (TUM) have discovered a mechanism to show how this is done.

Jan 30th, 2013

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A better way to culture central nervous cells

A protein associated with neuron damage in Alzheimer's patients provides a superior scaffold for growing central nervous system cells in the lab. The findings could have clinical implications for producing neural implants and offers new insights on the complex link between the apoE4 apolipoprotein and Alzheimer's disease.

Jan 29th, 2013

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Quadruplex DNA found in human cells

60 years after Watson and Crick's ground breaking paper described the double helix structure of DNA, researchers at the University of Cambridge have observed four-stranded DNA structures within human cells. The discovery could open the door to novel cancer therapies and a new era for personalised medicine.

Jan 29th, 2013

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Learning the alphabet of gene control

Scientists from Karolinska Institutet in Sweden have made progress in understanding how human genes are regulated. In their study they have identified the DNA sequences, which bound to over four hundred proteins controlling the expression of genes.

Jan 28th, 2013

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Computer scientists develop new way to study molecular networks

In biology, molecules can have multi-way interactions within cells, and until recently, computational analysis of these links has been "incomplete," according to T. M. Murali, associate professor of computer science in the College of Engineering at Virginia Tech. His group authored an article on their new approach to address these shortcomings.

Jan 25th, 2013

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Scientists discover genetic key to efficient crops

With projections of 9.5 billion people by 2050, humankind faces the challenge of feeding modern diets to additional mouths while using the same amounts of water, fertilizer and arable land as today. Cornell researchers have taken a leap toward meeting those needs by discovering a gene that could lead to new varieties of staple crops with 50 percent higher yields.

Jan 23rd, 2013

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Odd biochemistry yields lethal bacterial protein

While working out the structure of a cell-killing protein produced by some strains of the bacterium Enterococcus faecalis, researchers stumbled on a bit of unusual biochemistry. They found that a single enzyme helps form distinctly different, three-dimensional ring structures in the protein, one of which had never been observed before.

Jan 22nd, 2013

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A diffusion trap

Sticky spots on cell membranes hold onto the master regulator of cell polarity, helping to ensure that the regulatory protein accumulates in high enough concentrations to trigger cell polarity.

Jan 22nd, 2013

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