New research provides a rare 'picture' of the activity taking place at the single molecular level: visual evidence of the mechanisms involved when a cell transports mRNA (or messenger RNA) to where a protein is needed to perform a cellular function.
Imagine millions of jigsaw puzzle pieces scattered across a football field, with too few people and too little time available to assemble the picture. Scientists in the new but fast-growing field of computational genomics are facing a similar dilemma.
Scientists have captured new details of the biochemical interactions necessary for cell division -- molecular images showing how the enzyme that unwinds the DNA double helix gets drawn to and wrapped around its target. The research may suggest ways for stopping cell division when it goes awry.
By employing next generation DNA sequencing of genomes isolated from single cells, great strides are being made in the monumental task of systematically bringing to light and filling in uncharted branches in the bacterial and archaeal tree of life.
A new GBP10 million Innovation and Knowledge Centre (IKC), that will boost the UK's ability to translate the emerging field of synthetic biology into application and provide a bridge between academia and industry was announced yesterday.
Researchers have developed a technique for the rapid and reliable distinction between strains that can cause chronic infections and those that cannot. Using infrared light and artificial intelligence, the scientists present a sophisticated method for the prediction of disease progression.
Researchers at Memorial Sloan-Kettering Cancer Center, together with collaborators in Germany, have developed a new method for identifying the cell of origin of intracellular and secreted proteins within multicellular environments.
Photosynthesis takes place in specialized membrane systems, made up of stacked disks linked together by unstacked planar leaflets. An LMU team has now identified a protein that tucks the membrane in at the edge of each stack.
In Bolivia, in the largest continuous salt desert in the world, researchers from the Polytechnic University of Catalonia have found a bacterium that stores large amounts of PHB, a prized polymer. This biodegradable plastic is used by the food and pharmaceutical industries, for example to produce nanospheres to transport antibiotics.
Genetic mutations aren't the only thing that can keep a protein called PTEN from doing its tumor-suppressing job. Johns Hopkins researchers have now discovered that four small chemical tags attached (reversibly) to the protein's tail can have the same effect, and they say their finding may offer a novel path for drug design to keep PTEN working.