Scientists and engineers have developed synthetic gene circuits that program the functionality, performance, and behavior of living cells. These gene circuits hold great promise in medical and biotechnological applications, but to date, most circuits are constructed through a manner, which relies on a designer's intuition and is often inefficient. Researchers have addressed the challenge by constructing an integrated modeling framework for quantitatively describing and predicting gene circuit behaviors.
A recent study has presented a new way to advance the click chemistry. This is expected to be used in various areas, such as the synthetic chemistry of new drugs, development of functional high-molecules, and bio-imaging.
Biochemical engineers have used sequences of DNA molecules to induce shape-changing in water-based gels, demonstrating a new tactic to produce soft robots and 'smart' medical devices that do not rely on cumbersome wires, batteries or tethers.
Researchers have taken the first steps towards the development of a sensor for the detection of bacterial meningitis in real time by combining gravimetric sensors with synthetic antibodies giving, as a result, a sensitive, rapid and affordable method.
Scientists have identified the mechanism that allows fluorescent proteins to switch colour in two phases. They are thereby laying the groundwork for new applications in microscopy and functional analyses in biological research.