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Landing therapeutic genes safely in the human genome

Researchers predict and validate genomic safe harbors for therapeutic genes, enabling safer, more efficient and predictable gene and cell therapies.

Jan 24th, 2022

Researchers develop novel microscopic picoshell particles

Bioengineers have created a new type of petri dish in the form of microscopic, permeable particles that can dramatically speed up research and development timelines of biological products, such as fatty acids for biofuels.

Jan 21st, 2022

Scientists build 'valves' in DNA to shape biological information flows

Scientists have developed new biological parts that are able to shape the flow of cellular processes along DNA.

Jan 21st, 2022

Seek and ye shall find: comprehensive detection of on- and off-target mutations

Researchers design a software program that reliably detects and classifies a variety of intended and off-target mutations induced by a targeted genomic mutation strategy.

Jan 20th, 2022

Researchers track the lifespan and myriad functions of mRNA

It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus.

Jan 19th, 2022

Novel hydrogel promotes neural regeneration after spinal cord injury

Researchers have developed a multifunctional scaffold to effectively regulate the immune microenvironment after spinal cord injury and reduce secondary injury effects.

Jan 18th, 2022

Bone growth inspired 'microrobots that can create their own bone

Inspired by the growth of bones in the skeleton, researchers have developed a combination of materials that can morph into various shapes before hardening. The material is initially soft, but later hardens through a bone development process that uses the same materials found in the skeleton.

Jan 17th, 2022

Shape guides the growth of organoids

Bioengineers have developed new methods for successfully guiding the stem cells to grow into intestinal tissues with real-life 3D structure and function.

Jan 12th, 2022

Scientists expand CRISPR-Cas9 genetic inheritance control in mammals

Biologists achieve gene conversion in male mice, broadening potential for human disease research and environmental applications.

Jan 12th, 2022

Artificial intelligence predicts RNA and DNA binding sites to speed up drug discovery

Researchers developed an artificial intelligence-driven solution that uses data on the structure of RNA or DNA molecules to identify sites on them where interaction with potential drug candidates can occur. Knowledge of these binding sites allows pharmaceutical companies to discover new medications - including antiviral agents - in a much more focused and efficient manner.

Jan 11th, 2022

Genome research: Finding the invisible

Researchers have developed a method to extract more information from sequencing data. This will afford deeper insights into biology.

Jan 11th, 2022

Cancer therapy using on-site synthesis of anticancer drugs

An international research group has successfully treated cancer in mice using metal catalysts that assemble anticancer drugs together inside the body.

Jan 10th, 2022

Biotechnology could provide an environmentally more sustainable alternative to egg white protein production

Research shows that fungus-produced ovalbumin could have the potential to mitigate part of the environmental burden associated with chicken egg white powder. This is especially true when using low carbon energy sources in the production.

Jan 7th, 2022

Researchers develop a method that gives enzymes the ability to catalyze new-to-nature reactions

Scientists have developed a method by which certain enzymes can be coaxed into facilitating useful reactions that were never previously observed in the biological world, thereby widening their repertoire and opening possibilities for processes never before conducted by enzymes.